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epimerization

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
epimerization /epim·er·iza·tion/ (ĕ-pim″er-ĭ-za´shun) the changing of one epimeric form of a compound into another, as by enzymatic action.
epimerization
the changing of one epimeric form of a compound into another, as by enzymatic action.


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The epimerization strongly decreases the compound's biologic efficacy; the anabolic potency of TbOH-17[alpha] is only about 5% of that of TbOH-17[beta] (9), and the affinity to the recombinant human androgen receptor (rhAR) is reduced to about 4% (10).
 
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