Epimerase | definition of epimerase by Medical dictionary
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enzyme that catalyzes a change in asymmetric groups in substrates (epimers
) that have more than one center of asymmetry.
A class of enzymes catalyzing epimeric changes.
epimerase /epim·er·ase/ (ĕ-pim´ĕ-rās″) an isomerase that catalyzes inversion of the configuration about an asymmetric carbon atom in a substrate having more than one center of asymmetry; thus epimers are interconverted.
[EC 5.1] A class of enzymes catalyzing epimeric changes.
an isomerase that catalyzes the inversion of asymmetric groups in substrates (epimers) having more than one center of asymmetry.
References in periodicals archive
Decreased myo-inositol to chiro-inositol (M/C) ratios and increased M/C epimerase
activity in PCOS theca cells demonstrate increased insulin sensitivity compared to controls.
Under the agreement with Marukin Shoyu, Cytel receives the exclusive worldwide rights to make and use "GlcNAc 2" epimerase
in combination with its SNC Technology.
Molecular characterization of a first human 3(alpha [right arrow] beta)-hydroxysteroid epimerase
Clinical 1 No clinical abnormality 2 FNA 3 FNA 4 FNA 5 Epimerase
deficiency 6 Epimerase
deficiency 7 Epimerase
deficiency (mild) 8 FNA 9 FNA 10 FNA 11 Epimerase
deficiency (profound) 12 Epimerase
deficiency (transient) 13 Het D/G 14 Het D 15 Het D/G 16 Het D 17 Het D/G 18 Het D 19 No abnormality 20 FNA (a) To convert Gal concentrations to milligrams per deciliter, divide by 0.
Diagnosis: The epimerase
and kinase activities can both be measured in human lymphoblastoid cells (186), and total GNE activity can be measured in human leukocytes (187).