epimer


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epimer

 [ep″ĭ-mer]
one of two or more optical isomers that differ only in the configuration around one asymmetric carbon atom. adj., adj epimer´ic.

ep·i·mer

(ep'i-mĕr),
One of two molecules (having more than one chiral center) differing only in the spatial arrangement about a single chiral atom, for example, α-d-glucose and α-d-galactose (with respect to carbon-4).
See also: sugars. Compare: anomer.
[epi- + G. meros, part]

epimer

/ep·i·mer/ (ep´ĭ-mer) either of two optical isomers that differ in the configuration around one asymmetric carbon atom.

ep·i·mer

(ep'i-mĕr)
One of two molecules (having more than one chiral center) differing only in the spatial arrangement about a single chiral atom.
See: sugars
Compare: anomer
[epi- + G. meros, part]

epimer

one of two or more isomers which differ only in the configuration about one carbon atom.
References in periodicals archive ?
51 in compounds 4 and 5, respectively, denoting that 5 is the 25S epimer of 4 (25R) (Agrawal 2005) (Table 1).
One of those confounders is the C-3 epimer of (3-epi) 25(OH)[D.
8) showed that commonly used LC-MS/MS procedures may overestimate the 25(OH)D concentration when the C-3 epimer accounts for a substantial proportion of the circulating 25(OH)[D.
In the chimeric mouse urine only the epimer of VII (VIIc) could not be detected under the current instrumental conditions, but it should be noted that in humans VIIc is only a minor metabolite.
Schmidt's comments give the false impression that our recently published HPLC method (1) is unable to identify the presence of the C-3 epimer apart from 25(OH)[D.
Without chromatographic resolution of the 2 compounds, the epimer could mistakenly be reported as 25(OH)[D.
Epitestosterone (E), the 17[alpha] epimer of testosterone, is a naturally occurring steroid found in urine in concentrations similar to those of testosterone.
E is the 17a epimer of T and is present in urine in concentrations similar to T.
As it seems unlikely that the vitamin D sufficiency/insufficiency status of an individual would be altered by the presence of the epimer, it is not necessary to quantify the epimer in these subjects.
2]D, which may have a regulatory role in intestinal calcium transport (9);a metabolite hydroxylated at carbon C4 by CYP3A4, which may explain certain drug-induced disorders of bone, (10); and an epimer at carbon C3 in the A ring, a form that appears to have a relatively constant concentration throughout the human lifespan but has an unclear biological function after 1[alpha]-hydroxylation (11-13).
22R homohopanes are more abundant than 22S epimers and the 22S/(22S + 22R) homohopane ratio of oil shale samples is very low (Table 6).