epigenetic

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Related to epigenetically: Epigenetic regulation, Epigenetic inheritance

ep·i·ge·net·ic

(ep'i-jĕ-net'ik),
Relating to epigenesis.

epigenetic

/epi·ge·net·ic/ (-jĕ-net´ik)
1. pertaining to epigenesis.
2. altering the activity of genes without changing their structure.

epigenetic

(ĕp′ĭ-jə-nĕt′ĭk)
adj.
1. Of or relating to epigenetics.
2. Of or relating to epigenesis.

ep·i·ge·net·ic

(ep'i-jĕ-net'ik)
Relating to epigenesis.

epigenetic

Relating to inheritable changes in the pattern of gene expression caused by factors other than changes in the nucleotide sequence of genes. It is now recognized that cancer is caused both by genetic and epigenetic changes and that these two factors are intimately interrelated in the development of tumours.
References in periodicals archive ?
Identification of epigenetically silenced genes in human pancreatic cancer by a novel method "microarray coupled with methyl-CpG targeted transcriptional activation" (MeTA-array).
5) Animal studies have also implicated epigenetically modified dendritic cells in the transmission of allergic risk from mothers to offspring.
Reexpression of epigenetically silenced AML tumor suppressor genes by SUV39H1 inhibition.
Surprisingly, the scientists found some twins can become more epigenetically similar over time.
In summary, alcohol-induced epigenetically mediated changes in gene expression may underlie the brain pathology and adaptations in brain functioning (i.
Epigenetically affected Agouti mice, normally lean and brown-haired, become fat and blond (SN: 6/24/06, p.
HDAC inhibitors epigenetically modify the chromatin structure of tumour cells to cause their differentiation and programmed cell death (apoptosis) and are therefore considered to offer a mechanism of action that has the particular potential to halt tumour progression and induce tumour regression.
The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.
Most of these differentially methylated regions were found to be within CpG islands, the CpG-rich areas of euchromatin known to epigenetically regulate gene expression (Koestler et al.
Additional PTEN silencing may occur epigenetically, and thus combined, the PI3K pathway maybe activated in approximately 15%-20% of TNBC, with enrichment in the nonbasal expression type tumors.
2005), and a profound shift in epigenetically sensitive phenotypes (Kaminen-Ahola et al.