epigallocatechin gallate


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epigallocatechin gallate

Alternative pharmacology
A substance present in green tea that is an antioxidant, reduces blood pressure and lowers the total and low-density lipoprotein-cholesterol, while raising the high-density lipoprotein cholesterol.

epigallocatechin gallate

(ĕp″ĭ-găl′ō-kăt-ĕ-chĭn găl′lāt),

EGCg, EGCG

A polyphenol compound present in green tea that inhibits the growth of cancer cells in the laboratory. Its effect on patients with cancer is unknown.
References in periodicals archive ?
Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-[alpha].
These findings demonstrated a high anti-cancer activity of photodynamic therapy with green tea constituent, Epigallocatechin Gallate (EGCG), on TC-1 tumor cell implanted mice.
Green tea contains five types of catechins, namely gallocatechin, epicatechin, epigallocatechin, epicatechin gallate and epigallocatechin gallate, but the most potent of the group is the last one, epigallocatechin gallate, often referred to as EGCg, for short.
Green Tea and its extract epigallocatechin gallate (EGCG), Turmeric and its extract curcumin, Hawthorne and its flavonoid extract Grape skins and its extract resveratrol
With obesity becoming a greater problem in the United States, research has been conducted to study the weight loss and metabolic influences of green tea, specifically epigallocatechin gallate (EGCG).
A compound called methylated epigallocatechin gallate has been identified as responsible for the positive effect - the chemical is found in high concentrations in green tea and in far lower levels in regular processed teas.
Epigallocatechin gallate (EGCG) is the primary component thought to have cancer preventive effects.
This clinical trial assessed if the green tea flavonol, epigallocatechin gallate (EGCG), could rescue the deficits in cognition in adult mice with Down syndrome and in a pilot study involving human subjects with Down syndrome.
Inhibition of inducible nitric oxide synthase gene expression and enzyme activity by epigallocatechin gallate, a natural product from green tea.
2,2-Diphenyl-l-picryl-hydrazyl (DPPH*), [alpha]-hydroxy-1, 4-naphthoquinone (juglone), and epigallocatechin gallate (EGCG) [greater than or equal to] 95% were obtained from Sigma (Sigma-Aldrich GmbH, Steinheim, Germany).
Four compounds, epigallocatechin gallate (EGCG), delphinidin chloride, kaempferol, and punicic acid, were found to inhibit DHT-stimulated cell growth at concentrations of 10 [micro]M and above.
The most powerful of these catechins, Epigallocatechin gallate (EGCG), is a potent antioxidant that may offer substantial benefits for people with health problems.