epidermodysplasia

epidermodysplasia

 [ep″ĭ-der″mo-dis-pla´zhah]
faulty development of the epidermis.
epidermodysplasia verrucifor´mis the widespread and persistent (sometimes lasting decades) dissemination of verruca plana associated with a tendency to malignant degeneration. It typically begins in early childhood with the development of flat-topped papules that increase in number and coalesce to form large plaques, especially on the knees, elbows, and trunk. Familial occurrence and mental retardation are often associated with the disorder.

ep·i·der·mo·dys·pla·si·a

(ep'i-dĕr'mō-dis-plā'zē-ă),
Faulty growth or development of the epidermis.
[epidermis + G. dys-, bad, + plasis, a molding]

epidermodysplasia

/epi·der·mo·dys·pla·sia/ (-der″mo-dis-pla´zhah) faulty development of the epidermis.
epidermodysplasia verrucifor´mis  a condition due to a virus identical with or closely related to the virus of common warts, in which the lesions are red or red-violet and widespread, and tend to become malignant.

ep·i·der·mo·dys·pla·si·a

(ep'i-dĕr'mō-dis-plā'zē-ă)
Faulty growth or development of the epidermis.
[epidermis + G. dys-, bad, + plasis, a molding]

epidermodysplasia

see epidermal dysplasia.
References in periodicals archive ?
According to doctors, Bajandar suffers from epidermodysplasia verruciformis, a disease that is not contagious but incurable and surgeries only provide temporary relief.
Keywords: epidermodysplasia verruciformis, human papillomavirus, malignancy
Epidermodysplasia verruciformis (EV) is a rare, generalised, persistent, inherited disorder that predisposes the patient to widespread HPV infection and cutaneous malignancies.
It is anyways true for a few people who undergo from Epidermodysplasia Verruciformis 2, an acquired skin pathology characterised by eruptions of wart-like sores that may occur anywhere on the body.
Abul Bajandar, who has been suffering from rare genetic skin disease epidermodysplasia verruciformis also referred to as "Tree Man Disease", was successfully operated second time on Saturday at the Dhaka Medical College Hospital (DMCH).
Other etiologic factors for the development of SCCs are ionizing radiation, chronic inflammatory processes, human papillomavirus (HPV) infection (especially at anogenital sites, but in the setting of epidermodysplasia verruciformis, also in the face), and certain chemicals such as arsenic.
Objective To find out presence of nonmelanoma skin cancer (NMSC) in a series of 13 patients with diagnosis of epidermodysplasia verruciformis (EDV).
Increased risk of skin cancer associated with the presence of epidermodysplasia verruciformis human papillomavirus types in normal skin.
Patients with epidermodysplasia verruciformis have an immune defect that prevents recognition of HPV, resulting in severe skin infection and a 90% increase in NMSC risk (Pfister 2003).
5, 9) reported that cutaneous HPV and epidermodysplasia verruciformis (EV) could play a role in the pathogenesis of genital melanoma either as a direct and primary agent, via oncogenic interactions, or as a cofactor, via activation of melanocytes (melanosis) or chronic fibroinflammatory states (eg, lichen sclerosus).
Eight papers examine these developments from such perspectives as clinical manifestations of hyper IgE syndromes, the essential role of DOCK8 in humoral immunity, DOCK8 immune deficiency as a model for primary cytoskeletal dysfunction, and epidermodysplasia verruciformis and the susceptibility to HPV.
Favre M, Orth G, Majewski S, Baloul S, Pura A, Jablonska S: Psoriasis: A possible reservoir for human papillomavirus type 5, the virus associated with skin carcinomas of epidermodysplasia verruciformis.