According to doctors, Bajandar suffers from epidermodysplasia
verruciformis, a disease that is not contagious but incurable and surgeries only provide temporary relief.
verruciformis, human papillomavirus, malignancy
verruciformis (EV) is a rare, generalised, persistent, inherited disorder that predisposes the patient to widespread HPV infection and cutaneous malignancies.
It is anyways true for a few people who undergo from Epidermodysplasia
Verruciformis 2, an acquired skin pathology characterised by eruptions of wart-like sores that may occur anywhere on the body.
Abul Bajandar, who has been suffering from rare genetic skin disease epidermodysplasia
verruciformis also referred to as "Tree Man Disease", was successfully operated second time on Saturday at the Dhaka Medical College Hospital (DMCH).
Other etiologic factors for the development of SCCs are ionizing radiation, chronic inflammatory processes, human papillomavirus (HPV) infection (especially at anogenital sites, but in the setting of epidermodysplasia
verruciformis, also in the face), and certain chemicals such as arsenic.
Objective To find out presence of nonmelanoma skin cancer (NMSC) in a series of 13 patients with diagnosis of epidermodysplasia
Increased risk of skin cancer associated with the presence of epidermodysplasia
verruciformis human papillomavirus types in normal skin.
Patients with epidermodysplasia
verruciformis have an immune defect that prevents recognition of HPV, resulting in severe skin infection and a 90% increase in NMSC risk (Pfister 2003).
5, 9) reported that cutaneous HPV and epidermodysplasia
verruciformis (EV) could play a role in the pathogenesis of genital melanoma either as a direct and primary agent, via oncogenic interactions, or as a cofactor, via activation of melanocytes (melanosis) or chronic fibroinflammatory states (eg, lichen sclerosus).
Eight papers examine these developments from such perspectives as clinical manifestations of hyper IgE syndromes, the essential role of DOCK8 in humoral immunity, DOCK8 immune deficiency as a model for primary cytoskeletal dysfunction, and epidermodysplasia
verruciformis and the susceptibility to HPV.
Favre M, Orth G, Majewski S, Baloul S, Pura A, Jablonska S: Psoriasis: A possible reservoir for human papillomavirus type 5, the virus associated with skin carcinomas of epidermodysplasia