CCL24

(redirected from eotaxin-2)

CCL24

A gene on chromosome 7q11.23 that encodes a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. CCL24 binds CCR3; it is chemotactic for resting T lymphocytes, has some effect on neutrophils and none on monocytes or activated T lymphocytes; it is also a strong suppressor of colony formation by multipotential haematopoietic stem cells.
References in periodicals archive ?
Levels of interferon (IFN)-[gamma] (Endogen, Cambridge, MA, USA), interleukin (IL)-4 (Amersham, Buckinghamshire, UK), IL-5 Endogen), IL-13 (R&D Systems, Minneapolis, MN, USA), eotaxin (R&D Systems), eotaxin-2 (R&D Systems), and thymic stromal lympho-poietin (TSLP; R&D Systems) in the ear tissue supernatants were measured by enzyme-linked immunosorbent assay (ELISA) according to the manufacturers' instructions.
However, DINP significantly decreased the expression of eotaxin and eotaxin-2 compared with vehicle in the presence of intradermal Dp (p < 0.
0 Sensitivity, ng/L 200 1 j IGFBP-1 Eotaxin-2 (b) n 12/17 1/17 Average amount (SE) 5.
Both eotaxin-1 and eotaxin-2 are chemokines specific for eosinophils.