eotaxin

eotaxin

(ē'ō-tak-sin),
A chemokine with chemoattractant properties for eosinophils, but not for leukocytes.
[eosinophil + G. taxis, orderly arrangement, + -in]

CCL11

A gene on chromosome 17q21.1-q21.2 that encodes eotaxin-1, a CC-type cytokine, which is characterised by two adjacent cysteines and, as with all cytokines, is involved in immunoregulatory and inflammatory processes. Eotaxin-1/CCL11 binds CCR3, is chemotactic for eosinophils—but not mononuclear cells or neutrophils—and is involved in eosinophilic type inflammatory responses (e.g., atopic dermatitis, allergic rhinitis, asthma and parasitic infections).

eotaxin

(e-o-toks'in) [Gr. eos, dawn (rose-colored) + (chemo)taxin]
A chemokine that specifically attracts eosinophils to particular tissues (e.g., to bronchial tissues in asthma or to the skin in contact dermatitis). Tumor necrosis factor alpha stimulates its release. See: chemotaxis; cytokine
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References in periodicals archive ?
The quantitative measurement of Eotaxin protein from mouse serum was carried out through Simple Step ELISA(tm) kit (Catalogue # Ab201277) purchased from Abcam.
Airway infammation and eotaxin in exhaled breath condensate of patients with severe persistent allergic asthma during omalizumab therapy.
Zinc suppressed airway inflammation in asthmatic rats: effects of zinc on generation of eotaxin, MCP-1, IL-8, IL-4, and IFN-y.
We also saw a notable decrease in eotaxin levels in acute-phase samples.
2007) Effect of exercise training on plasma visfatin and eotaxin levels.
3] also caused greater increases in BAL CXCL1, IL-6, IL-2, eotaxin (CCL11), CSF3, IL-1a, IL-10, IL-12 (p40), CXCL10, LIF, RANTES, CXCL9, and CCL4 in the same cohort of [O.
In non-castrated mice, GM-CSF, eotaxin, lL1b, IL13, and MIP-1b were more expressed in [OMEGA]3-fed mouse tumors.
IL-4 plays essential role in IgE dependent mast cell activation, up-regulation of eotaxin expression, induction of vascular cell adhesion molecules on vascular endothelium, and migration of eosinophils, basophils, monocytes, and T lymphocytes to inflammatory loci.
Global Markets Direct's, 'C-C Chemokine Receptor Type 3 (C-C CKR-3 or Eosinophil Eotaxin Receptor or CD193 or CCR3) - Pipeline Review, H1 2016', provides in depth analysis on C-C Chemokine Receptor Type 3 (C-C CKR-3 or Eosinophil Eotaxin Receptor or CD193 or CCR3) targeted pipeline therapeutics.
Objective: To investigate the serum levels of Interleukin (IL)-17 and eotaxin levels and the relationship between serum IL-17, eotaxin and pulmonary function in asthmatic patients with allergic rhinitis.
Recent research identified a mediator called eotaxin and revealed its essential role in obstructive lung disease.