eosinophilic granuloma

granuloma /gran·u·lo·ma/ (gran″u-lo´mah) pl. granulomas, granulo´mata   an imprecise term for (1) any small nodular delimited aggregation of mononuclear inflammatory cells, or (2) such a collection of modified macrophages resembling epithelial cells, usually surrounded by a rim of lymphocytes.

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actinic granuloma  a round lesion with a raised border seen on skin chronically exposed to sunlight.

granuloma annula´re  a benign, self-limited disease consisting of round granulomas of the dermis in groups, with papules or nodules, mainly seen in young girls.

apical granuloma  modified granulation tissue containing elements of chronic inflammation, located adjacent to the root apex of a tooth with infected, necrotic pulp.

coccidioidal granuloma  secondary coccidioidomycosis.

eosinophilic granuloma 

1. Langerhans cell histiocytosis.

2. a disorder similar to eosinophilic gastroenteritis, with localized nodular or pedunculated lesions of the submucosa and muscle walls, especially of the pyloric area of the stomach, caused by infiltration of eosinophils, but without peripheral eosinophilia or allergic symptoms.

3. anisakiasis.

granuloma fissura´tum  a firm, red, fissured, fibrotic granuloma of the gum and buccal mucosa of an edentulous alveolar ridge between the ridge and cheek; caused by an ill-fitting denture.

infectious granuloma  one due to a specific microorganism, as tubercle bacilli.

granuloma inguina´le  a granulomatous venereal disease, usually seen in dark-skinned people, marked by purulent ulceration of the external genitals, caused by Calymmatobacterium granulomatis.

lethal midline granuloma  a rare lethal necrotizing granuloma that destroys the midface; it is nearly always preceded by longstanding nonspecific inflammation of the nose or nasal sinuses, with purulent, often bloody discharge.

lipoid granuloma  xanthoma.

lipophagic granuloma  granuloma with loss of subcutaneous fat.

midline granuloma  lethal midline g.

paracoccidioidal granuloma  paracoccidioidomycosis.

peripheral giant cell reparative granuloma  giant cell epulis.

pyogenic granuloma  a benign, solitary nodule resembling granulation tissue, found anywhere but often in the mouth, usually at the site of trauma as a tissue response to nonspecific infection.

reticulohistiocytic granuloma  a solitary reticulohistiocytoma that is not associated with systemic involvement.

sarcoid granuloma  the granuloma seen with sarcoidosis.

swimming pool granuloma  one that complicates injuries sustained in swimming pools, attributed to Mycobacterium balnei, often healing spontaneously over time.

trichophytic granuloma  tinea corporis, usually on the lower legs, due to Trichophyton infecting hairs at the site, with raised, circumscribed, boggy granulomas, scattered or in chains; lesions are slowly absorbed, or undergo necrosis, leaving scars.

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eosinophilic granuloma

n.

A lesion having numerous histiocytes that may contain Langerhans granules, eosinophils, and pockets of necrosis. It is usually a solitary bone lesion but may develop in the lung.

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eosinophilic granuloma.

1 a simple or multiple growth in the bone or lung characterized by numerous eosinophils and histiocytes. Eosinophilic granulomas occur most frequently in children and adolescents.

2 See anisakiasis.

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eosinophilic granuloma,

n See granuloma, eosinophilic.

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eosinophilic

staining readily with eosin; pertaining to eosinophils or to eosinophilia.

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cartilaginous eosinophilic streaks

streaks of eosinophilic matrix in cartilage. Some are normal zones of development, others represent areas of matrix degeneration and osteochondrosis.

eosinophilic chemotactic factor

a primary mediator of type I anaphylactic hypersensitivity, it is an acidic peptide (molecular weight 500) released by mast cells, which attracts eosinophils to areas where it is present.

equine eosinophilic chronic dermatitis

acanthosis and hyperkeratosis accompanied by eosinophilic granulomas in pancreas and other epithelial organs.

feline eosinophilic granuloma complex

a collective name given to the lesions of eosinophilic ulcer, eosinophilic plaque (below), and linear granuloma because of similarities in histopathology, clinical course and occasionally simultaneous occurrence in the cat.

eosinophilic granuloma

nodules or plaques that occur on skin or oral mucosa of dogs. Usually not pruritic, but oral lesions can cause some difficulties in eating. The cause is unknown. See also feline eosinophilic granuloma complex (above), equine nodular collagenolytic granuloma.

eosinophilic intestinal granuloma

see angiostrongyluscostaricensis.

eosinophilic lung disease

see pie syndrome.

eosinophilic meningitis

see gnathostomaspinigerum.

eosinophilic meningoencephalitis

see sodium chloride poisoning, angiostrongyluscantonensis.

eosinophilic myocarditis

in cattle may be observed in normal animals at slaughter. Histologically there is a predominant eosinophil invasion of the heart muscle. May be accompanied by similar lesions in skeletal muscles.

eosinophilic plaque

well-defined, raised, ulcerated and extremely pruritic lesions that occur on the skin of cats, usually on the abdomen or hindlegs. There are large numbers of eosinophils present in the dermis and sometimes peripheral blood. See also eosinophilic granuloma (above), feline eosinophilic granuloma complex (above).

eosinophilic pneumonia

see pie syndrome.

eosinophilic ulcer

a well-defined ulceration, usually on the upper lip of cats overlying the canine tooth, which is shallow initially but can become extremely erosive and sometimes neoplastic. Mildly irritating to the cat. Called also indolent ulcer, rodent ulcer. See also feline eosinophilic granuloma complex (above).

Bilateral eosinophilic ulcer. By permission from Kummel BA, Color Atlas of Small Animal Dermatology, Mosby, 1989

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eosinophilic granuloma

Medtalk A benign clinical form of histiocytosis X, characterized by circumscribed cystic osseous lesions in children and adolescents composed of eosinophils and histiocytes. See Langerhans' cell histiocytosis.