eosinophilic gastroenteritis

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Related to eosinophilic gastritis: eosinophilic gastroenteropathy

gastroenteritis

 [gas″tro-en″tĕ-ri´tis]
inflammation of the lining of the stomach and intestine. Psychologic causes may include fear, anger, and other forms of emotional upset. Allergic reactions to certain foods can cause the condition, as can irritation by excessive use of alcohol. Severe gastroenteritis, with such symptoms as headache, nausea, vomiting, weakness, diarrhea, and gas pains, may result from various infectious and contagious diseases, such as typhoid fever, influenza, and food poisoning.
eosinophilic gastroenteritis a disorder, commonly associated with intolerance to specific foods, marked by infiltration of the mucosa of the small intestine and frequently the stomach by eosinophils, with edema but without vasculitis and by eosinophilia of the peripheral blood. Symptoms depend on the site and extent of the disorder.

e·o·sin·o·phil·ic gas·tro·en·ter·i·tis

disorder comprising abdominal pain, malabsorption, often obstructive symptoms, associated with peripheral eosinophilia and areas of eosinophilic infiltration of the stomach, small intestine, and colon. May have an allergic etiology and responds to elimination diet in some patients; corticosteroid therapy is also effective.

eosinophilic gastroenteritis

a disorder marked by infiltration of the mucosa of the small intestine by eosinophils, with edema but without vasculitis, and by eosinophilia of the peripheral blood. Symptoms, including abdominal pain, diarrhea, nausea, fever, and malabsorption, depend on the site and extent of the disorder. The stomach is also frequently involved. The disorder is commonly associated with intolerance to specific foods.

eosinophilic gastroenteritis

A rare (about 300 cases reported in the world literature) heterogeneous condition characterised by abundant eosinophils in the lamina propria, especially of the stomach and less commonly of the small and large intestine.

Aetiology
Idiopathic or associated with allergies (e.g., asthma, atopic eczema, food allergy—usually to milk or soy protein), connective tissue disease (e.g., scleroderma, polymyositis, and dermatomyositis), Crohn’s disease, and parasites (e.g., anisakiasis).

Clinical findings
Nausea, vomiting, diarrhoea, weight loss, abdominal pain (linked to ingestion of specific foods), fever, rebound tenderness, mesenteritis.

Lab
Often with increased eosinophils in peripheral blood.
 
Pathology
Eosinophils in mucosa, fibrosis of muscularis propria with thickening and rigidity with outlet obstruction.

Management
May respond to elimination diet; up to 90% respond to corticosteroids.

e·o·sin·o·phil·ic gas·tro·en·ter·i·tis

Disorder comprising abdominal pain, malabsorption, often obstructive symptoms, associated with peripheral eosinophilia and areas of eosinophilic infiltration of the stomach, small intestine, and colon.

gastroenteritis

inflammation of the lining of the stomach and intestine. The clinical manifestations are vomiting and diarrhea. See also gastritis.

canine hemorrhagic gastroenteritis
an acute syndrome of vomiting and bloody diarrhea with dehydration and marked hemoconcentration. If not treated vigorously, it may lead to circulatory failure and death in a short time. The cause is unknown.
eosinophilic gastroenteritis
a chronic segmental disease of the alimentary tract characterized by a variety of signs depending on the location of the lesion but including vomiting, or diarrhea or melena or hematochezia. Occurs in dogs, particularly German shepherd dogs, rarely in cats, and in horses. Diarrhea, weight loss and a protein-losing enteropathy result. A hypersensitivity to ingested allergens is the suggested cause. The diagnostic lesion is the aggregation of eosinophils in the intestinal wall. See also eosinophilic gastritis.
transmissible viral gastroenteritis of pigs
see transmissible gastroenteritis.
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