enterohemorrhagic Escherichia coli


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en·ter·o·hem·or·rhag·ic Esch·e·rich·i·a co·li (EHEC),

enterohemorrhagic strains of Escherichia coli, commonly of the serotype 0157:H7; produces a toxin resembling that produced by Shigella; associated with damage to the epithelium, ischemia of the bowel, and necrosis of the colon. Apparently responsible for a hemorrhagic form of colitis without fever, which can be very severe; spread primarily by contaminated beef and poultry. May also cause microangiopathic hemolytic anemia, renal failure, and the hemolytic uremic syndrome.

enterohemorrhagic Escherichia coli (EHEC)

[-hem′ôraj′ik]
a strain of E. coli that causes hemorrhage in the intestines. The organism produces shiga toxin, which damages bowel tissue, causing intestinal ischemia and colonic necrosis. Symptoms are stomach cramping and bloody diarrhea. An infectious dose may be as low as 10 organisms. Spread by contaminated beef, unpasteurized milk and juice, sprouts, lettuce, and salami, as well as contaminated water, the infection can be serious although there may be no fever. Treatment consists of antibiotics and maintenance of fluid and electrolyte balance. In advanced cases, surgical removal of portions of the bowel may be required.

enterohemorrhagic Escherichia coli

EHEC Any of the E coli serotypes–eg O29, O39, O145 that produces shiga-like toxins, causing bloody inflammatory diarrhea, evoking a HUS. See Escherichia coli O157:H7, Hemolytic uremic syndrome.

en·ter·o·hem·or·rhag·ic Esch·e·rich·i·a co·li

(EHEC) (en'tĕr-ō-hem-ŏr-aj'ik esh-ĕ-rik'ē-ă kō'lī)
Strain of E. coli, usually of the serotype 0157:H7; produces a toxin resembling that produced by Shigella; associated with damage to the epithelium, ischemia of the bowel, and necrosis of the colon. Apparently responsible for a hemorrhagic form of colitis without fever, which can be very severe and is spread primarily by contaminated beef. May also cause microangiopathic hemolytic anemia, renal failure, and the hemolytic uremic syndrome.
References in periodicals archive ?
Chromosomal dynamism in progeny of outbreak-related sorbitol-fermenting enterohemorrhagic Escherichia coli O157:NM.
Recycling of Shiga toxin 2 genes in sorbitol-fermenting enterohemorrhagic Escherichia coli O157:NM.
Fifty strains used for SNP typing of enterohemorrhagic Escherichia coli O157 * Year of SF status Strain ID isolation Illness and serotype TB182A ([double dagger]) 1991 D SF O55:H7 CB9615 ([double dagger]) 2003 D SF O55:H7 493/89 ([double dagger]) 1989 HUS SF O157:[H.
Evolution of enterohemorrhagic Escherichia coli hemolysin plasmids and the locus for enterocyte effacement in Shiga toxin-producing E.
Identification of a novel fimbrial gene cluster related to long polar fimbriae in locus of enterocyte effacement-negative strains of enterohemorrhagic Escherichia coli.
act] HUSEC039 - 1c -- HUSEC040 - -- 2c HUSEC041 - -- 2 * HUSEC, hemolytic uremic syndrome-associated enterohemorrhagic Escherichia coli, EHEC, enterohemorrhagic E.
Distribution of the secondary type III secretion system locus found in enterohemorrhagic Escherichia coli O157:H7 isolates among Shiga toxin-producing E.
3-kb plasmids of an enterohemorrhagic Escherichia coli O157:H7 derived from Sakai outbreak.
toxB gene on pO157 of enterohemorrhagic Escherichia coli O157: H7 is required for full epithelial cell adherence phenotype.
Enterohemorrhagic Escherichia coli O157:H7 produces Tir, which is translocated to the host cell membrane but is not tyrosine phosphorylated.
Decreased adherence of enterohemorrhagic Escherichia coli to HEp-2 cells in the presence of antibodies that recognize the C-terminal region of intimin.