Similar reductions occurred in association with obesity, DM, MS, and NAFLD, promoting alterations in the intestinal barrier and enterocytes
leading to increased intestinal permeability.
Decreased activities of antioxidant enzymes in intestine or enterocytes
with oxidized lipids have been found using various models (Ringseis et al.
Reports have also shown that lectins bind to complementary carbohydrates present on the surface of enterocytes
, for example in glycolipids and glycoproteins of the brush border membrane and as a result of enterocyte
atrophy, the nutrient absorption surface area becomes reduced and the transport of nutrients through the epithelium gets impeded, which leads to inhibited growth of animals.
Bcl2 expression was taken as positive when expression was noted in the enterocyte
cytoplasm or in the nuclear membrane.
Villous ischaemia-reperfusion injury in haemodynamic instability and hypotension leads to epithelial morphological disruption, apoptotic and necrotic cell loss, blunted villous height, and shedding of enterocytes
into the gut lumen.
Dietary iron is extracted into duodenal enterocytes
at the luminal or villous pole via the divalent metal transporter 1 (DMT 1).
functional adaptation following intestinal resection.
Reduced heparan sulfate accumulation in enterocytes
contributes to protein-losing enteropathy in a congenital disorder of glycosylation.
The uptake of dietary non-haem iron in the gastrointestinal (GI) tract requires protein-mediated transport and two separate enterocyte
pathways have been identified, namely the Divalent Metal Transporter-1 (DMT-1) and the Integrin-Mobilferrin pathway (IMP),8 DMT1 requires iron in the ferrous form ([Fe.
These genes affect the ability of the pathogen to produce and secrete proteins known as "LEE," short for "locus of enterocyte
Then, once inside the enterocyte
, they are hydrolysed to amino acids by cytoplasmic peptidases and pass into the bloodstream.
Once inside the enterocyte
, iron is transported to the basolateral side of the cell where iron can be transported out of the cell into the blood.