However, if FDA could be persuaded to increase the maximum avobenzone concentration to 5%, and allow it in combination with ensulizole
, titanium dioxide and zinc oxide, this would open up new formulation opportunities," he insisted.
Under the regulation, companies would also be able to combine avobenzone with either zinc oxide or ensulizole
, which Dr.
This leaves only 10 ingredients that could be formulated in today's US sunscreen formulations--namely octocrylene, homosalate, octinoxate, octisalate and ensulizole
for UVB protection and avobenzone, oxybenzone, titanium dioxide and zinc oxide for UVA protection.
The following combinations with avobenzone are still not allowed: ZnO, TiO2, ensulizole
, meradimate, PABA and padimate-O.
Meradimate and ensulizole
(restrictions when used with avobenzone);
No decision was made on the combination of avobenzone with zinc oxide, titanium dioxide, ensulizole
, meradimate, PABA and padimate O.
Ingredients: The combination of avobenzone (up to 3%) with both zinc oxide (up to 25%) and ensulizole
(up to 4%) is now allowed.
these crystalline UV filters included the Benzophenones, PABA, Avobenzone, DEA Methoxy Cinnamate and Ensulizole
New ingredients and new combinations of ingredients are both patentable, such as L'Oreal's avobenzone and octocrylene and ScheringPlough's avobenzone, zinc oxide and ensulizole
The name changes are required for four active ingredients: meradimate for methyl anthranilate, octinoxate for octyl methoxycinnamate, octisalate for octyl salicylate and ensulizole
for phenylbenzimidazole sulfonic acid.