S100A12

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S100A12

A gene on chromosome 1q21 that encodes a member of the S100 family of proteins, which contain 2 EF-hand calcium-binding motifs and as a group regulate cell cycle progression and differentiation and other cellular processes. The S100A12-encoded protein may be involved in calcium-dependent signal transduction pathways; its regulatory effect on cytoskeletal components may modulate neutrophil activities and trigger the release of cytokines.
References in classic literature ?
Surely there is no better way, to stop the rising of new sects and schisms, than to reform abuses; to compound the smaller differences; to proceed mildly, and not with sanguinary persecutions; and rather to take off the principal authors by winning and advancing them, than to enrage them by violence and bitterness.
It will but enrage him the more and make our sufferings the worse.
It must enrage the other servants to see her deporting herself as if she were quite the lady.
Failure but tended to further enrage the mad creature.
She knew that at best it could but enrage him and yet she meant to sell her life dearly, for she felt that she must die.