enkephalins


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Related to enkephalins: encephalitis, Endorphins, somatostatin, substance P

en·keph·a·lins

(en-kef'ă-linz),
Pentapeptide endorphins, found in many parts of the brain, that bind to specific receptor sites, some of which may be pain-related opiate receptors; hypothesized as endogenous neurotransmitters and nonaddicting analgesics. Metenkephalin is Tyr-Gly-Gly-Phe-Met; leuenkephalin has Leu in place of Met; proenkephalin has Pro in place of Met.

enkephalins

See ENDORPHINS.

enkephalins,

n.pl either of the two pentapeptides produced in the body that bind neuroreceptors in brain to alleviate pain.

en·keph·a·lins

(en-kef'ă-linz)
Pentapeptide endorphins, found in many parts of the brain.
References in periodicals archive ?
Like anandamide, the endorphins and enkephalins play a role in the healthy brain and are probably involved in immune function, motor control, and pain relief, Evans speculates.
produces enkephalin locally in the targeted sensory neurons to block pain signals before they are transmitted through the spinal cord to the brain.
Thus the diencephalic endorphin and mesencephalic enkephalin neurons stimulate the serotonin neurons at the bulbus (28-30) The serotoninergic neurons at the dorsal horn of the spinal cord stimulate the intermediate neurons at the dorsal horn.
The researchers also found that enkephalin, the natural drug-like chemical produced in that same brain region, surged when rats began to eat the candy-coated morsels, too.
11) catalyses the degradation of a variety of renal and CNS-active peptides, including substance P, bradykinin, enkephalins and atrial natriuretic peptides.
Ischemic preconditioning increases the bioavailability of cardiac enkephalins.
increased ER-beta (Oliveri, 1998), ER-alpha (Ogawa, 1999), dysfunctional amagdyla (Szczpka, 1998) (Wilson, 2001), stress induced damage to frontal lobes (Royalty, 1990) (Wilson, 2001), low COMT (Goldberg, 1995) (Largerspetz, 1999), low enkephalins (Lachman, 1998) low cortisol (Decaire, 1999), substance P (DeFlipe, 1998) and P-choloramphetamine (Gianutos, 1975).
He theorizes that in responding to the placebo, the patient's body produces its own pain-relieving chemicals called endorphins and enkephalins that mimic morphine.
Positive emotions like happiness produce natural substances within the body, called endorphins and enkephalins.
Eating energy-dense foods with a lot of fat or sugar trigger the release of endorphins and enkephalins, the brain's natural opioids which, in turn, stimulate a squirt of dopamine, generating a feeling of reward.
12,13] A strong correlation between the acupuncture analgesia and stimulated release of endogenous opioid peptides, such as [beta] endorphin and enkephalins, has been well estab lished.