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enkephalin |
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enkephalin /en·keph·a·lin/ (en-kef´ah-lin) either of two pentapeptides (leu-enkephalin and met-enkephalin) occurring in the brain and spinal cord and also in the gastrointestinal tract; they have potent opiate-like effects and probably serve as neurotransmitters.
enkephalin (enkef´  lin), n one of two pain-relieving pentapeptides produced in the body. enkephalin either of two naturally occurring pentapeptides (methionine enkephalin and leucine enkephalin) isolated from the brain, which have potent opiate-like effects and probably serve as neurotransmitters. They are classified as endorphins. |
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Nicholas Bodor and his colleagues at the University of Florida in Gainesville sandwiched a naturally occurring pain-relief protein called enkephalin between a fatty acid and a molecule that becomes positively charged in the presence of enzymes found in the brain. Indeed, endorphin and enkephalin production is stimulated by exercise. According to Isabel Karle, the largest molecule so far analyzed by the direct method is the nervous system peptide, enkephalin, which consists of five amino acids and contains 230 carbon, nitrogen and oxygen atoms. |
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