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endotoxin |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.03 sec. |
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endotoxin /en·do·tox·in/ (en´do-tok″sin) a heat-stable toxin present in the intact bacterial cell but not in cell-free filtrates of cultures of intact bacteria. Endotoxins are lipopolysaccharide complexes that occur in the cell wall; they are pyrogenic and increase capillary permeability.en´dotoxic
endotoxin [en′dōtok′sin] Etymology: Gk, endon + toxikon, poison a toxin contained in the cell walls of some microorganisms, especially gram-negative bacteria, that is released when the bacterium dies and is broken down in the body. Fever, chills, shock, leukopenia, and a variety of other symptoms result, depending on the particular organism and the condition of the infected person. Compare exotoxin. endotoxin, n toxin present in the cell walls of bacteria that is released after the bacteria has died. May cause chills, fever, leukopenia, and shock depending on the bacterial species and the health of the infected person. endotoxin (en´dōtok´sin), n a nondiffusible lipid polysaccharide-polypeptide complex formed within bacteria (some gram-negative bacilli and others); when released from the destroyed bacterial cells, endotoxin is capable of producing a toxic manifestation within the host. endotoxin a heat-stable toxin present in the intact bacterial cell but not in cell-free filtrates of cultures of intact bacteria. It is the lipopolysaccharide (LPS) of gram-negative outer membranes. Also called O antigen. It is pyrogenic and increases capillary permeability through stimulation of tumor necrosis factor alpha release. endotoxin Bacterial endotoxin, lipid A Microbiology A heat-stable lipopolysaccharide on the outer coat of gram-negative bacteria–eg, those causing cholera, meningitis, pneumonia, plague, whooping cough, et al Clinical Leukopenia,
thrombocytopenia, fever, chills, hemorrhagic shock, dec resistance to infection How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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To determine the influence of endotoxin on the incidence of acute respiratory illness during the first 2 years of life, we carried out a longitudinal follow-up study, beginning at birth, of 332 children born in Prince Edward Island, Canada. However, endotoxemia in liver transplant recipients has been associated with graft failure and a high mortality rate (4,5), and in gram-negative bacterial infections, the physiologic effects of endotoxin may persist after adequate antimicrobial drug treatment. An immune system underexposed to endotoxins may not be able to combat unknown invaders later on like allergens (allergy-causing molecules). |
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