endothelial dysfunction


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endothelial dysfunction

Failure of the lining of blood vessels and body cavities to carry out normally any of their complex functions including the production of NITRIC OXIDE and ENDOTHELIN-1. Endothelial dysfunction reduces flow-dependent widening of arteries (vasodilatation).
References in periodicals archive ?
Although it is known that epithelial dysfunction can bring a plethora of chronic illnesses, it remains unclear exactly how salt-induced endothelial dysfunction may affect the brain in the long run.
10 Of them, inflammation and endothelial dysfunction seems to have a basic contributing factor in the progression of DN.
In patients with MetS, the effect of the major CV risk factors, not included in the MetS definition, on endothelial dysfunction is not well known.
In this study, we aimed to examine whether there is an endothelial dysfunction in patients with Familial Mediterranean Fever (FMF) and the relationship between EMPs and activation of the disease in children with FMF.
Endothelial dysfunction (ED) is an early, usually asymptomatic phase of endothelial cell damage which results in disruption of its numerous functions.
The changes, visible on Tesla MRI using Tl, T2, and FLAIR weighted images, are probably caused by diabetes-related endothelial dysfunction, he said.
Endothelial dysfunction is possibly the earliest event in the process of atherosclerotic lesion formation, hence, the concept that assessment of endothelial function may be a useful tool to identify preclinical atherosclerosis.
A recent animal study confirmed that salidroside protects arteries from endothelial dysfunction, (31) an early pathological event that can lead to the development of high blood pressure, heart attack, and stroke.
It is characterized by endothelial dysfunction and impaired paracrine interaction between activated stellate hepatocytes and sinusoidal endotheliocytes, sinusoidal remodeling and capillarization, as well as development of the collateral microcirculation [10].
sup][5] Endothelial dysfunction is a likely pathological mechanism that is common to both these comorbidities and ED.
OSA leads to CVD through several pathological mechanisms if left untreated [9]; an important mechanism is through vascular endothelial dysfunction characterized by impaired nitric oxide (NO) production, which can ultimately lead to atherosclerosis [10].
Preeclampsia is a disease of the human species, described more than a century ago, of unknown cause, which shares with atherosclerosis risk factors, biochemical abnormalities, endothelial dysfunction and a multifactorial origin.

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