endonuclease


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endonuclease

 [en″do-noo´kle-ās]
an enzyme that cleaves internal bonds of polynucleotides.
restriction e's enzymes that cleave large DNA molecules at specific sequences of four to six nucleotides. See also recombinant dna technology.

en·do·nu·cle·ase

(en'dō-nū'klē-ās),
An enzyme (phosphodiesterase) that cleaves the internal phosphodiester bonds in a DNA molecule, thus producing DNA fragments of varying size. Compare: exonuclease.

endonuclease

/en·do·nu·cle·ase/ (-noo´kle-ās) any nuclease specifically catalyzing the hydrolysis of interior bonds of ribonucleotide or deoxyribonucleotide chains.
restriction endonuclease  an endonuclease that hydrolyzes DNA, cleaving it at an individual site of a specific base pattern.

endonuclease

(ĕn′dō-no͞o′klē-ās′, -āz′, -nyo͞o′-)
n.
Any of a group of enzymes that catalyze the hydrolysis of bonds between nucleotides in the interior of a DNA or RNA molecule.

endonuclease

an enzyme that cleaves or hydrolyzes phosphodiester bonds within a polynucleotide chain. Compare exonuclease.

en·do·nu·cle·ase

(en'dō-nū'klē-ās)
A nuclease (phosphodiesterase) that cleaves polynucleotides (nucleic acids) at interior bonds, thus producing polynucleotide or oligonucleotide fragments of varying size.
Compare: exonuclease

endonuclease

a NUCLEASE that cleaves PHOSPHODIESTER BONDS from within nucleic acid molecules. See also RESTRICTION ENDONUCLEASE, compare EXONUCLEASE.

en·do·nu·cle·ase

(en'dō-nū'klē-ās)
A nuclease (phosphodiesterase) that cleaves polynucleotides (nucleic acids) at interior bonds.

endonuclease

(en´dōnoo´klēās´),
n an enzyme (nuclease) that cleaves polynucleotides at interior bonds, producing polynucleotide or oligonucleotide fragments.

endonuclease

a nuclease that cleaves internal bonds of polynucleotides.

restriction endonuclease
References in periodicals archive ?
The integrity of the nptII and cry3Bb1 coding regions and transgene cassettes were evaluated by digestion with the restriction endonuclease HindIII, which cleaves at the 5' and 3' ends of each of the transgene cassettes.
The use of restriction endonucleases to measure mitochondrial DNA sequence relatedness in natural populations III.
All the partial digestion were done as mentioned above, the short time for incubating endonuclease SwaI produced fragment which are the sum of two, three, four or more fragments, the size of joined fragments 10W-12W was 332.
The results obtained with the use of endonucleases Hinc II, Acc I, and PflM I showed that the cutting sites were identical to FV3 in 100% (10/10) of the isolates from the current study.
The team led by EMBL head Stephen Cusack analyzed crystals of endonuclease from the 2009 pandemic influenza strain using the high intensity X-ray beams at the European Synchrotron Radiation Facility (ESRF).
panamensis also possesses a gene that codes for this enzyme, which upon being expressed in a recombinant manner presents endonuclease activity under conditions known to be present during the apoptotic process.
psbC-trnS primers and endonuclease HaeIII combination) from the rest of the accessions (Fig.
AP endonuclease 1 (Ape1) is the major mammalian abasic endonuclease, accounting for > 95% of the total cellular AP site incision activity (Demple and Harrison 1994).
Gene flow among six populations of the collared lizard (Crotaphytus collaris) was estimated using restriction endonuclease analysis of a segment of the mitochondrial genome.
For each restriction endonuclease, each fragment profile was compared against those in related species (J.
bluebird bio also has discovery research programmes utilising megaTAL/homing endonuclease gene editing technologies with the potential for use across the company's pipeline.
patent 9,458,439 claims the method of introducing chromosomal modifications at a locus by induction of double-stranded DNA cleavage using a chimeric restriction endonuclease and non-homologous end joining recombination (NHEJ).