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endonuclease

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endonuclease /en·do·nu·cle·ase/ (-noo´kle-ās) any nuclease specifically catalyzing the hydrolysis of interior bonds of ribonucleotide or deoxyribonucleotide chains.
restriction endonuclease  an endonuclease that hydrolyzes DNA, cleaving it at an individual site of a specific base pattern.

en·do·nu·cle·ase (nd-nkl-s, -z)
n.
Any of a group of enzymes that catalyze the hydrolysis of phosphodiester bonds between nucleic acids in a DNA molecule or RNA sequence.

endonuclease,
an enzyme that cleaves or hydrolyzes phosphodiester bonds within a polynucleotide chain. Compare exonuclease.

endonuclease
(en´dōnoo´klēās´),
n an enzyme (nuclease) that cleaves polynucleotides at interior bonds, producing polynucleotide or oligonucleotide fragments.

endonuclease
a nuclease that cleaves internal bonds of polynucleotides.

restriction endonuclease


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Although the intrinsic pathway involves early activation of caspase-9, and the extrinsic pathway is mediated through caspase-8, both lead to activation of the "executioner" caspase-3 and a variety of proteases and endonucleases.
Increased expression of apurinic and apyrimidinic (AP) endonuclease (~ 5-fold) indicates possible activation of DNA repair processes (He et al.
These include restriction endonucleases for cleaving DNA and ligases for joining the fragments, recombinases that can execute a large variety of DNA cleavage and joining reactions.
 
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