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endogenous opioid

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endogenous opioid,
an opiate-like substance, such as an endorphin, produced by the body.

opioid
1. any synthetic narcotic that has opiate-like activities but is not derived from opium.
2. denoting naturally occurring peptides, e.g. enkephalins, that exert opiate-like effects by interacting with opiate receptors of cell membranes.

endogenous opioid
opioid receptors
specific receptor sites for opioids, named for the drugs which have a high binding affinity for them. The main ones are mu (morphine), kappa (opioid agonist-antagonists such as pentazocine) and delta (enkephalin endogenous opioids). Subtypes exist and others, such as sigma and epsilon, have been identified.


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Induction of human mast cell degranulation by opiates and endogenous opioid peptides: evidence for opiate and non-opiate receptor participation.
an endogenous opioid, increases during every moderate exercise session, (11) we hypothesized that a shorter exercise program of 2 weeks may be sufficient to enhance secondary antibody response.
The cause of POI is not clear, but release of endogenous opioids in response to the trauma of surgery is believed to be involved.
 
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