endocardial cushion defect

per·sis·tent a·tri·o·ven·tric·u·lar ca·nal

a condition that is caused when the atrial and ventricular septa fail to meet, as in normal development, resulting in a low atrial and a high ventricular septal defect or a common atrioventricular canal.

endocardial cushion defect

[en′dōkär′dē·əl]
any cardiac defect resulting from the failure of the endocardial cushions in the embryonic heart to fuse and form the atrial septum. It is common in Down syndrome. See also atrial septal defect, congenital cardiac anomaly.
References in periodicals archive ?
In an exploratory analysis, we considered seven clinical diagnostic groupings of CHDs: a) conotruncal defects (tetralogy of Fallot and transposition of great vessels); b) endocardial cushion and mitrovalve defects (EMD; endocardial cushion defect and hypoplastic left heart syndrome); c) pulmonary artery and valve defects (PAV; pulmonary valve atresia and stenosis and pulmonary artery anomalies); d) tricuspid valve defects (TVD; tricuspid valve atresia and stenosis and Ebstein's anomaly); e) aortic artery and valve defects (aortic valve stenosis and coarctation of aorta); f) ventricular septal defects (VSD); and g) patent ductus arteriosis in births > 2,500 g (Gilboa et al.
An echocardiogram showed an endocardial cushion defect, single atrium, right-sided aorta, pulmonary hypertension, tricuspid regurgitation and situs inversus with levocardia.
5 ppm 1,100 ppm L-Transposition (left chest) 1 0 Great vessel defect 1 0 Pulmonary valve defect 1 0 Atrial septal defect 4 7 Ventricular septal defects Subaortic 2 1 Muscular 1 4 Endocardial cushion defect 0 1 Aortic valve defect 0 2 No.