end-stage renal disease


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end-stage renal disease

 
chronic renal failure that is irreversible; at this stage serum creatinine and blood urea nitrogen (BUN) levels continue to rise and there is uremia with impairment of all body systems.

re·nal fail·ure

loss of renal function, either acute or chronic, that results in azotemia and syndrome of uremia.

end-stage renal disease

End-organ disease, end-stage renal failure The decompensated stage of chronic renal failure, defined as renal insufficiency of a degree that requires dialysis or kidney transplantation for survival  Epidemiology 30% of ESRD is linked to DM and HTN, the most common causes of ESRD; ESRD is seen in kidneys subjected to chronic dialysis Costs ESRD programs for 200,000 Pts–0.08% of US population, cost $6 x 109–0.8% of US health care budget Complications Infection, possibly due to impaired macrophage Fc-receptor function  Management Kidney transplantation, see there Prognosis 1-yr survival of graft, ±94%; half-life from living donor grafts, ±22 yrs, from cadaveric grafts, ±14 yrs.

End-stage renal disease (ESRD)

Total kidney failure; chronic kidney failure is diagnosed as ESRD when kidney function falls to 5-10% of capacity.
References in periodicals archive ?
Two hundred seventy-nine patients with end-stage renal disease and hyperphosphatemia were randomly assigned to an intervention group or a control group.
Two other factors likely to contribute to the high rates of TB are renal failure (1-3) and the high prevalence of diabetes mellitus in patients from the Indian subcontinent, a group in whom we have noted a high incidence of end-stage renal disease (6).
SAN FRANCISCO--Women with end-stage renal disease have an increased rate of benign breast calcifications, but these do not interfere with the accurate interpretation of their mammograms, Dr.