Lower the machine needle down into the fabric precisely at the dart end point
, just one thread away from the fold (8).
Piolitazone Lowers Cardiovascular Event Risk in Diabetes Patients With Chronic Kidney Disease Pioglitazone Placebo (n = 274) (n = 323) Primary end point
24% 31% Secondary end point
15% 21% Source: Journal of the American Society of Nephrology Note: Table made from bar graph.
Although the development of in vitro methods is occurring more systematically than ever before, it continues to be a slow and uncertain procedure to model the complex biological processes that underlie toxicological assessments for end points
such as subchronic and chronic toxicity, reproductive toxicity, and carcinogenicity.
Given the lack of time and funding needed to study biomarkers extensively, there has been a strong push among biopharmaceutical industry players to explore innovative study designs that optimize the use of biomarkers as surrogate end points
The extension of efforts like these to incorporate toxicological and biological end points
critically defines and distinguishes toxicogenomic databases, and several key initiatives will be discussed here.
IP end points
are likely to gain visibility in the small and medium enterprise (SME) customer segment in the immediate future.
Proposed end points
include assessment of gamete quality, fecundity, gross pathology of gonads, measurement of relative gonad weight (gonadal somatic index), and measurement of vitellogenin levels (a widely used bio-marker of estrogen exposure in fish) (8,27).
They will improve hazard characterization through the use of biomarkers of response or effect with mechanistic linkage to end points
Breakthrough Twin Beam Technology Enables Dedicated TEM and STEM Sample Preparation with More Artifact Free Sample Clarity and Precise End Point
Rambus digital controllers are available as root complex, switch port, end point
and hybrid (end point
/root complex) device types.
Codian products are end point
agnostic and deliver each conference participant the best possible audio and video quality; this makes them ideal for Chinese organizations that require frequent face-to-face communication across the country or have diverse end point
equipment or connection speeds.
Shenoy and his colleagues set out to shorten the process by focusing on the end point
rather than processing every step along the way.