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enchondromatosis

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enchondromatosis /en·chon·dro·ma·to·sis/ (en-kon″dro-mah-to´sis) hamartomatous proliferation of cartilage cells within the metaphysis of several bones, causing thinning of the overlying cortex and distortion of the growth in length; it may undergo malignant transformation.
en·chon·dro·ma·to·sis (n-kndr-m-tss, nkn-dr-)
n.
A congenital but nonfamilial disorder involving tubular bones, especially of the hands and feet, and characterized by a neoplasmlike proliferation of cartilage in the metaphyses that cause distorted growth in length or pathological fractures. Also called dyschondroplasia, Ollier's disease.

enchondromatosis
[en′kəndrō′mətō′sis]
Etymology: Gk, en + chondros, cartilage, oma, tumor, osis, condition
a congenital disorder characterized by the proliferation of cartilage within the extremity of the shafts of bones, causing thinning of the cortex and distortion in length. Also called dyschondroplasia, Ollier's disease. Compare Maffucci's syndrome.

enchondromatosis
a condition in humans characterized by hamartomatous proliferation of cartilage cells within the metaphysis of several bones, causing thinning of the overlying cortex and distortion of the growth in length. Called also dyschondroplasia, Ollier's disease.


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Malignant change in a previously benign tumour is largely restricted to conditions such as multiple exostoses (diaphyseal aclasis) and multiple enchondromatosis or Ollier's disease, where a relatively slow-growing chondrosarcoma develops in middle age.
Differential considerations for this condition include multiple exostosis, enchondromatosis, multiple epiphyseal dysplasia, Turner's syndrome without LWD, achondroplasia, chondroectodermal dysplasia, and hypoparathyroidism.
Maffucci's syndrome is a congenital disorder characterized by multiple hemangiomas and enchondromatosis that can be present at birth or can appear during infancy or later in childhood.
 
 
 
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