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encephalomalacia

   Also found in: Encyclopedia, Wikipedia 0.03 sec.
encephalomalacia /en·ceph·a·lo·ma·la·cia/ (en-sef″ah-lo-mah-la´shah) softening of the brain.
en·ceph·a·lo·ma·la·cia (n-sf-l-m-lsh)
n.
Softening of brain tissue, usually caused by vascular insufficiency or degenerative changes. Also called cerebromalacia.

encephalomalacia
literally, softening of the brain but the term is used to include degenerative diseases of the brain generally. Leukoencephalomalacia refers to the white matter, polioencephalomalacia to the gray matter. The syndrome associated with encephalomalacia is primarily one of loss of function including somnolence, blindness, ataxia, head pressing, circling and terminal coma.

degenerative encephalomalacia
includes nigropallidal encephalomalacia, leukoencephalomalacia.
focal symmetrical encephalomalacia
a subacute form of enterotoxemia due to Clostridium perfringens type D in sheep which are partly immune to the toxin. Clinical signs are the dummy syndrome of aimless wandering, head pressing, blindness and incoordination. Most affected sheep die after an illness of about 7 days.
nigropallidal encephalomalacia

encephalomalacia
Neurology Softening of brain tissue, usually due to ischemia or infarction


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Several neurologic conditions were considered in the differential diagnosis, including other viral encephalomyelitides (rabies, Aujesky disease, Borna disease, EHV-1 myeloencephalopathy, WEEV, and WNV encephalomyelitis), bacterial meningitis, listeriosis, leukoencephalomalacia, lead poisoning, equine protozoal myeloencephalitis, nigropallidal encephalomalacia, botulism, and verminous encephalitis.
Autopsies of laboratory-confirmed WN meningoencephalitis cases revealed perivascular hemorrhages, ectasis of ventriculi of the brain, foci of encephalomalacia, dislocation of the brain trunk (30% of cases), and hydropericarditis with flabbiness of the cardiac muscle.
 
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