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encainide

   Also found in: Dictionary/thesaurus, Wikipedia 0.01 sec.
encainide /en·cai·nide/ (en-ka´nīd) a sodium channel blocker that acts on the Purkinje fibers and myocardium; used as the hydrochloride salt in treatment of life-threatening arrhythmias.
encainide
an antiarrhythmic drug that blocks Na+ conduction; used as the hydrochloride in the treatment of ventricular arrhythmias.

encainide
Enkaid® Cardiology An antiarrhythmic that was removed from the market as it causes arrhythmias and ↑ mortality. See CAST. Cf Flecainide.


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Schultz, deputy FDA commissioner for policy, told the Senate committee that two drugs approved to correct abnormal heart rhythms, encainide and flecainide, subsequently were used off-label for irregular heart rhythms during a heart attack - a use that was supported by several journal articles.
Study patients taking encainide (marketed as Enkaid by Bristol Laboratories in Evansville, Ind.
7%; 56/730) was seen in patients treated with encainide or flecainide (Class 1C antiarrhythmics) compared with that seen in patients assigned to placebo (3.
 
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