All naturally-occurring proteins are enantiomerically
pure because the amino acid building blocks that comprise proteins exist as single enantiomers.
They compared polycarbonate based on an enantiomerically
resolved IBP monomer with the same material made from a racemic 50/50 mixture of right-handed and left-handed IBP.
Industrial chemists have also recruited legions of microorganisms and their enzymes to convert raw materials into enantiomerically
The senior author recently became fully aware of the following strengths and weaknesses of the previously known lipase-catalyzed (S)-selective acetylation: (i) Enantiomerically
pure (R)-2-methyl-1-alkanols can be reliably obtained from their racemic mixtures, although the maximally attainable yield (or recovery) of (R)-alcohols of [greater than or equal to] 98% ee is limited to 50% or, more specifically [less than or equal to] 25% if E = 10, [less than or equal to] 35% if E = 20, and [less than or equal to] 45% if E = 100, where E (enantiomeric ratio or selectivity factor) = ln[(1 - C)(1 - ee)]/ ln[(1 - C)(1 + ee)] and C and ee are the extent of conversion and the enantiomeric excess of the unreacted alcohol, respectively.
This is in part because of the legal and ethical problems associated with the administration of a Schedule 1 controlled drug and specifically the difficulties in obtaining enantiomerically
pure reference compounds for both MDMA and MDA.
Recent Advances in the Synthesis of Enantiomerically
The goal of this work is to develop powerful synthetic approaches for the selective C-C bond activation and demonstrate that it has the potential to be a general principle in organic synthesis for the regio-, diastereo- and even enantiomerically
enriched preparation of adducts despite that C-C single bonds belong among the least reactive functional groups in chemistry.
68) The unique structure of 18 as a chiral allene evoked interest of chemists, and its absolute configuration was determined as R by Pirkle's synthesis of enantiomerically
The increasing demand for enantiopure drugs has led to the need for the preparation of new enantiomerically
Starting from enantiomerically
resolved trans-1,2-cyclohexanediamine, we initially targeted tridentate, C2-symmetric NHC-ligand precursors with two back-bonding hydroxy groups which are available via reductive amination and subsequent ring closing reaction with triethyl-orthoformate.
We have found that Sharpless-Katsuki complex is able to oxidize different cyclobutanones resulting in enantiomerically
Feringa has made efficient use of 5-menthyl-oxy-2(5H)-furanones to provide enantiomerically
pure synthons through "crystallization induced epimerization".