EMX2

(redirected from empty spiracles homeobox 2)

EMX2

A gene on chromosome 10q26.1 that encodes a transcription factor which, in co-operation with EMX1, generates the boundary between the roof and archipallium in the developing brain. EMX2 is expressed in embryonic and adult olfactory neuroepithelia, where it forms a complex with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelia and is downregulated by HOXA1.