2) Embryonal rhabdomyosarcomas
have a poor prognosis irrespective of therapy, (4,5) as seen in the present case.
5: Immunohistochemical staining of embryonal rhabdomyosarcoma
Sukov and coworkers (11) found ALK gene rearrangements in 67% of tumors in a series that included 21 cases of IMTs of the urinary bladder, but found no such ALK gene rearrangement in the other tumors among 32 non-IMTs tested, including 16 leiomyosarcomas and 3 embryonal rhabdomyosarcomas
In this article, the author reports a case of embryonal rhabdomyosarcoma
of the temporal bone with cranial nerve palsies and extension into the parapharyngeal space.
In 1998, at age 11 months, he was diagnosed with embryonal rhabdomyosarcoma
of the right maxilla and underwent partial maxillectomy and temporal bone resection, followed by chemotherapy (vinblastine) and radiation therapy.
The histopathologic features of the biopsy specimen were consistent with an embryonal rhabdomyosarcoma
We recommend that embryonal rhabdomyosarcoma
be ruled out to avoid overly aggressive treatment of these patients.
is the most common histologic variant seen in childhood; a large proportion of them arise in the head and neck-most commonly in the orbit, the nasopharynx, and the ear.