dense-core granule

(redirected from electron dense granule)

dense-core granule

A round structure—“black” inside, “lighter” near the granule’s membrane—seen by electron microscopy which contains chromogranin and other proteins in various configurations. Dense-core granules serve as ultrastructural evidence of neuroendocrine differentiation.
References in periodicals archive ?
Plasma membrane had undergone shrinkage and developed finger- like outgrowths Electron dense granules could be seen in the space formed between membranes which was a sign of toxicity.
Rare electron dense granules and microfilaments were seen in these adipocytic cells.
Although rare electron dense granules were identified ultrastructurally in the adipocytic cells, the relative lack of ultrastructural findings in the adipocytic cells may reflect a sampling phenomenon ("needle in a haystack") whereby the fat represents most of the cytoplasmic volume, effectively dispersing cytoplasmic organelles over a larger cell volume.

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