elastase


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elastase

 [e-las´tās]
an enzyme capable of catalyzing the digestion of elastic tissue.

e·las·tase

(ē-las'tās),
A serine proteinase hydrolyzing elastin; other elastase-like enzymes have been identified, for example, pancreatic elastase (pancreatopeptidase E) and leukocyte elastase (lysosomal or neutrophil elastase), with different sequences and kinetic parameters; all have fairly broad specificities.

elastase

/elas·tase/ (e-las´tās) see pancreatic elastase.

elastase

(ĭ-lăs′tās, -tāz)
n.
Any of a class of enzymes that catalyze the hydrolysis of elastin, especially one that is found in pancreatic juice.

elastase

an enzyme that cleaves bonds adjacent to neutral amino acids in elastin.

elastase

(1) Pancreatic elastase, EC 3.4.21.11. 
(2) Leukocyte elastase, EC 3.4.21.37.

e·las·tase

(ĕ-las'tās)
A serine proteinase hydrolyzing elastin.

elastase

an enzyme capable of catalyzing the digestion of elastic tissue.
References in periodicals archive ?
Compounds 2-11 were tested on their ability to alter bacterial growth, biofilm formation, Quorum Sensing process, and elastase activity of P.
A method to determine the influence of the distortion of the helix on the resistance against enzymatic degradation is the use of elastase as a degrading enzyme.
Antineutrophil cytoplasmic antibodies reacting with human neutrophil elastase as a diagnostic marker for cocaine-induced midline destructive lesions but not autoimmune vasculitis.
Fecal pancreas elastase 1 was measured in nonprocessed stool samples with a commercially available ELISA (ScheBo[R] Biotech AG).
In normal wounds, elastase and other proteases do a good job of breaking down dying tissue and clearing debris from the site," says Kel Cohen, director of the Division of Plastic and Reconstructive Surgery at the MCV Wound Healing Center.
Staining with antibodies against myeloperoxidase, chloroacetate-esterase, and neutrophilic elastase revealed no loss of the respective antigens in the myeloid population.
When this virus attacks the heart, it triggers the production of an enzyme called elastase that destroys heart cells and creates scar tissue," said Marlene Rabinovitch, MD, head of cardiovascular research at HSC.
This enzyme, called neutrophil elastase, is what causes the emphysema, and you don't have to be a smoker to get it (usually when one is in the 30s or 40s).
Zemaira, a human-derived alpha-1 proteinase inhibitor, acts to inhibit the activity of another protein, neutrophil elastase, which, left unchecked, can degrade the lining of the lungs and lead to pulmonary disease.
We believe CTX-4430's ability to reduce neutrophil elastase in the airways of CF patients has the potential to preserve lung function in CF patients, irrespective of patient-specific CF gene mutation," said Greg Duncan, President and CEO of Celtaxsys.
The effects of treatment in the rats were assessed by biochemical (articular elastase, MPO, LPO, GSH, catalase, SOD and NO), inflammatory mediators (IL-1[beta], IL-6, TNF-[alpha], IL-10, IFN-[gamma] and [PGE.