eicosanoids


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ei·co·sa·noids

(ī'kō-să-noydz),
The physiologically active substances derived from arachidonic acid, that is, the prostaglandins, leukotrienes, and thromboxanes; synthesized via a cascade pathway.
[G. eicosa-, twenty, + eidos, form]

ei·co·sa·noids

(ī-kō'să-noydz)
The physiologically active substances derived from arachidonic acid (e.g., the prostaglandins, leukotrienes, and thromboxanes); synthesized through a cascade pathway.
[G. eicosa-, twenty, + eidos, form]

eicosanoids

A general term for a range of modified polyunsaturated fatty acids, products of the metabolism of arachidonic acid. They are hormones and include prostaglandins, prostacyclins, thromboxanes and leukotrienes.

eicosanoids

a family of compounds derived from arachidonic acid (eicosatetraenoic acid). Includes prostaglandins, prostacyclin and thromboxanes, the principal mediators of inflammation.
References in periodicals archive ?
2]-X-null mice are protected from asthma, accompanied by decreased levels of pulmonary [omega]6 AA-derived eicosanoids.
sativa exerts its anti-inflammatory action may be related to its ability to inhibit eicosanoid generation.
Counteraction--DGLA and EPA derived eicosanoids directly counteract their AA derived counterparts.
Owing to the correlation between eicosanoids and endothelial cancer development (Bogatcheva et al.
Like omega 3, omega 6 is vital and plays an important role in heart health and maintaining levels of 'good' cholesterol, as well as in the function of eicosanoids.
albicans have been reported to produce eicosanoids particularly prostaglandin itself and/or in the presence of AA which is greater in biofilms.
5, 2, 5, and 16 h, aliquots were taken out of the samples to allow for each 10-12 replicates of MxP Broad Profiling, MxP Catecholamines, and MxP Eicosanoids as described below.
It has been shown that eicosanoid synthesis from PUFAs is increased in tumour cells [36] and that the relative proportion of n-3 and n-6 PUFAs in the cellular membranes is one factor which determines the types of eicosanoids that are generated [5].
3) Inflammatory mediators include the eicosanoids, biologically active lipids formed from arachidonic acid by cyclo-oxygenases, lipoxygenases or epoxygenases.
Moreover, eicosanoids are lipid mediators produced from 20-C fatty acids, especially ARA, EPA and DHLA, present in the plasmatic membrane of the cells that compose the affected tissues and immune cells (ROWLEY et al.
In general eicosanoids derived from n-6 PUFA are pro-inflammatory, while eicosanoids derived from n-3 PUFA are anti-inflammatory.
The pro-inflammatory "bad" eicosanoids are produced by arachidonic acids (AA).