eflornithine hydrochloride


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eflornithine hydrochloride

[eflôr′nithēn]
an inhibitor of the enzyme ornithine decarboxylase, applied in creams by females over age 12 to limit unwanted facial hair growth and administered by injection to treat the meningoencephalitic stage (sleeping sickness) of a protozoal infection caused by Trypanosoma brucei.
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In a 16-week study 10 African American men with a 2-year or longer history of severe razor bumps--pseudofolliculitis barbae of severity grade 3 or higher--applied eflornithine hydrochloride 13.
Chemicals which are projected to record double-digit growth through 2005 due to their novel or improved performance include coenzyme Q10, which combines antioxidant and exfoliant action; poly hydroxy acid, a hydroxy acid with a reduced risk of skin irritation; eflornithine hydrochloride, a hair growth retardant with new commercial applications; finasteride, a hair growth stimulant and a wide range of botanical and herbal extracts which have crossed over from the nutraceuticals industry.
Chemicals which are projected to record double-digit growth through 2005 due to their novel or improved performance include coenzyme Q10, which combines antioxidant and exfoliant action; poly hydroxy acid, a hydroxy acid with a reduced risk of skin irritation; eflornithine hydrochloride, a hair growth retardant with new commercial applications; finasteride, a hair-growth stimulant; and a wide range of botanical and herbal extracts which have crossed over from the nutraceutical industry and bring with them an established reputation of safety and health benefits.
A total of 106 women were treated with placebo or twice-daily eflornithine hydrochloride in doses of 5%, 10%, or 15% in a double-blind study.
9% of eflornithine hydrochloride that is clinically proven to slow down facial hair growth in women -- it does not stop the growth.