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effective half-life

   Also found in: Dictionary/thesaurus, Financial, Encyclopedia, Wikipedia 0.01 sec.
effective half-life
n.
See half-life.

effective half-life (ehl),
the time required for a radioactive element in an animal body to be diminished by 50% as a result of radioactive decay and biologic elimination. The effective half-life is equal to the product of the biologic half-life (bhl) and the radioactive half-life (rhl) divided by the sum of the bhl and the rhl: ehl |m= (bhl × rhl)/(bhl + rhl). See also biologic half-life.

effective half-life,


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For example, low doses of vitamin C are retained in the body and have an effective half-life of somewhere between eight and forty days.
In the liver, chemicals can be secreted into the bile and transported into the gut, where they are reabsorbed into the portal blood, thereby increasing the effective half-life for systemic clearance.
These extend to efficacy and safety, but also to important issues in drug development such as stabilization and the extension of effective half-life without affecting bioactivity," said Mr.
 
 
 
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