edrophonium


Also found in: Wikipedia.

edrophonium

 [ed″ro-fo´ne-um]
a cholinergic used in the form of the chloride salt as a curare antagonist and diagnostic agent in myasthenia gravis.

edrophonium

/ed·ro·pho·ni·um/ (ed″ro-fo´ne-um) a cholinergic used in the form of the chloride salt as a curare antagonist and as a diagnostic agent in myasthenia gravis.

edrophonium

A drug that inactivates the enzyme CHOLINESTERASE that breaks down ACETYLCHOLINE. It is used as a test for MYASTHENIA GRAVIS, a disease in which the action of acetyl choline is impaired. The brand name is Tensilon.

edrophonium

a cholinergic used in the form of the chloride salt as a curare antagonist; used in the edrophonium challenge test to diagnose myasthenia gravis. See also tensilon.
References in periodicals archive ?
A test dose of edrophonium to assess whether anticholinesterase therapy may be of benefit is generally recommended.
Test results from a complete blood count, biochemistry profile, whole-body radiographs, needle electromyography of the leg muscles, and an edrophonium challenge test were within reference limits.
Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium atropine.
Separation and detection of a mixture of 4 cationic inhibitors--tacrine, edrophonium, and tetramethyl- and tetraethyl-ammonium chloride--was accomplished within 70 s with a multiplexed screening device combining flow injection analysis and microchip CE separation.
The working diagnosis is myasthenia gravis, although there is no response to edrophonium and nystagmus is not common in myasthenia.
She was given an edrophonium test and her symptoms improved.
Antagonism of rapacuronium using edrophonium or neostigmine: pharmacodynamics and pharmacokinetics.
51] Since then, apomorphine has mainly been used as a diagnostic tool to predict or confirm dopaminergic responsiveness in parkinsonian syndromes in a manner similar to that of edrophonium in myasthenia gravis[55,81] and as an alternative in the treatment of advanced PD complicated by otherwise drug-resistant motor complications.
Tensilon--or, generically, edrophonium choride--has the power to restore almost normal muscular function almost instantly, in a matter of moments.
The common diagnostic test is using the anticholinesterase edrophonium (tensilon test) or neostigmine for reversal of muscle weakness.
An edrophonium test was positive with reversal of neck weakness to 5/5 power.