edetate


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Related to edetate: Edetate calcium disodium, Edetate disodium

edetate

 [ed´ĕtāt]
USAN contraction for ethylenediaminetetraacetate, a salt of ethylenediaminetetraacetic acid (EDTA); the salts include edetate disodium calcium, used in the diagnosis and treatment of lead poisoning, and edetate disodium, used in the treatment hypercalcemia because of its affinity for calcium.

ed·e·tate

(ed'ĕ-tāt),
USAN-approved contraction for ethylenediaminetetraacetate, the anion of ethylenediaminetetraacetic acid; various edetates are used as chelating agents to carry cations in (for example, ferric sodium edetate as an iron ion carrier) or out (for example, sodium edetate for calcium or heavy metal ion removal).

edetate

/ed·e·tate/ (ed´ĕ-tāt) USAN contraction for ethylenediaminetetraacetate, a salt of ethylenediaminetetraacetic acid (EDTA); the salts include e. calcium disodium, used in the diagnosis and treatment of lead poisoning, and e. disodium, used in the treatment of hypercalcemia because of its affinity for calcium.

ed·e·tate

(ed'ĕ-tāt)
Contraction for ethylenediaminetetraacetate approved by the U.S. Adopted Names Council.

edetate (eˑ·d·tāt),

n Scientific name:C10H14N2Na2O8·2H2O of EDTA; uses: treats cardiovascular disease, hypercalcemia, pathologic calcification; precautions: can cause renal tubular necrosis, acute renal failure, acute hypocalcemia, tetany, cardiac arrhythmias, bone marrow depression, vasculitis, and exfoliative dermatitis. Also called
disodium edetate.

edetate

any salt of ethylenediamine tetra-acetic acid (EDTA), including edetate disodium calcium, used in the diagnosis and treatment of lead poisoning, and edetate disodium, used in the treatment of poisoning with lead and other heavy metals, and, because of its affinity for calcium, in the treatment of hypercalcemia.
References in periodicals archive ?
Plans for TACT2 include targeting the population of patients who received the greatest benefits from edetate disodium treatment - those with a prior heart attack and diabetes.
Edetate calcium disodium forms stable chelates with a number of metals, but it is primarily used for lead overdose, either alone or in combination with dimercaprol.
5 mg/kg IM); calcium glubionate (100 mg/kg PO); calcium gluconate (100 mg/kg IM); supplemental fluids (45 mL/kg SC; Normosol-R, Hospira, Inc, Lake Forest, IL, USA); doxycycline (60 mg/kg IM; Vibravenos formulation, Pfizer Laboratories, London, Ontario, Canada); vitamins A, D, and E (3300 IU/kg IM; Northwest Pharmacy and Compounding Center, Houston, TX, USA); and edetate calcium disodium (35 mg/kg IM; calcium disodium versenate, 3M Pharmaceuticals, Northridge, CA, USA).
Each vial of EMEND for Injection for intravenous administration contains 188 mg of fosaprepitant dimeglumine equivalent to 115 mg of fosaprepitant and the following inactive ingredients: edetate disodium (14.
Deaths resulting from hypocalcemia after administration of edetate disodium: 2003-2005.
It has been shown that recovery of serum calcium concentrations following an acute lowering with edetate calcium disodium (EDTA) is unaffected in patients taking pamidronate (a bisphosphonate similar to alendronate) chronically for osteoporosis (13).
Dimercaprol is either used alone (arsenic, gold, and acute mercury) or combined with edetate calcium disodium (lead).
Davis FA, Becker FO, Michael JA, Sorensen E: Effect of intravenous sodium bicarbonate, disodium edetate (Na2EDTA), and hyperventilation on visual and oculomotor signs in multiple sclerosis.
Although calcium disodium edetate is an excellent choice for treatment of heavy-metal toxicosis, it is usually administered intramuscularly, which was not compatible with the long-term course of this study.