edatrexate

edatrexate

Oncology An antimetabolic anticancer agent in clinical trials
References in periodicals archive ?
Effect of vehicles and penetration enhancers on the in vitro and in vivo percutaneous absorption of methotrexate and edatrexate through hairless mouse skin.
SRI International medicinal chemists first synthesized PDX as a potential improved analog of edatrexate, an earlier antifolate developed by SRI International and MSKCC.
PDX was first synthesized by SRI International medicinal chemists as a potential improved analog of edatrexate, an earlier anti-folate developed by SRI International and MSKCC.