eczema vaccinatum

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1. any superficial inflammatory process involving primarily the epidermis, marked early by redness, itching, minute papules and vesicles, weeping, oozing, and crusting, and later by scaling, lichenification, and often pigmentation.
2. atopic dermatitis.

Eczema is a common allergic reaction in children but it also occurs in adults, usually in a more severe form. Childhood eczema often begins in infancy, the rash appearing on the face, neck, and folds of elbows and knees. It may disappear by itself when an offending food is removed from the diet, or it may become more extensive and in some instances cover the entire surface of the body. Severe eczema can be complicated by skin infections. Childhood eczema may persist for several years or return after the child is older. Persons suffering from childhood eczema may develop another allergic condition later, most often hay fever or asthma.
Cause and Treatment. Eczema is sometimes caused by an allergic sensitivity to foods such as milk, fish, or eggs. Inhalant allergens such as dust and pollens rarely cause eczema. Treatment involves the use of soothing baths, moisturizing creams, topical steroids, and oral antihistamines to alleviate itching. See also allergy.
eczema herpe´ticum disseminated herpes simplex (see kaposi's varicelliform eruption).
eczema margina´tum tinea cruris.
eczema vaccina´tum disseminated vaccinia (see kaposi's varicelliform eruption).

eczema vaccinatum

The spreading of vaccinia virus to localized areas of skin, or to the entire body, in patients recently vaccinated against smallpox. This reaction is a rare complication of smallpox vaccination, occurring in about 40 per million of newly vaccinated individuals. It usually occurs in people with pre-existing eczema and is occasionally fatal.
See also: eczema


Moritz (born Moritz Kohn), Hungarian dermatologist in Austria, 1837-1902.
Kaposi sarcoma - a multifocal malignant neoplasm. Synonym(s): multiple idiopathic hemorrhagic sarcoma
Kaposi varicelliform eruption - a rare complication of vaccinia superimposed on atopic dermatitis, with generalized vesicles and papulovesicles and high fever. Synonym(s): eczema vaccinatum
References in periodicals archive ?
People with active atopic dermatitis (eczema), or who have outgrown it, and those with whom they currently live cannot receive smallpox vaccinations because of the risk of eczema vaccinatum.
Over 27 million Americans may have a defect in their skin's barrier function which elevates their risk for eczema vaccinatum -- a severe and sometimes fatal reaction to the smallpox vaccine.
However, the federal Centers for Disease Control and Prevention (CDC) was recently notified that a child had contracted eczema vaccinatum, a potentially deadly illness that can manifest with a generalized skin rash similar to smallpox, following accidental contact with an open skin lesion on a relative who had recently been vaccinated for smallpox using a live vaccinia virus vaccine.
Peter Elias, Professor of Dermatology at the University of California, San Francisco, last year's recipient of the Society for Investigative Dermatology's Montagna award for outstanding research, urges two simple steps to reduce the risk of eczema vaccinatum (EV):
ADVN is a nationwide research group that seeks to reduce the risk of eczema vaccinatum ("EV"), a severe and potentially deadly complication of smallpox immunization.