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eczema vaccinatum

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eczema vac·ci·na·tum (vks-ntm)
n.
A form of generalized vaccinia supervening upon an existing atopic dermatitis and accompanied by a high fever, malaise, and enlargement of the lymph nodes.

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A risk for eczema vaccinatum occurs in about 1 in 100,000 primary vaccinations (20), which can result in serious consequences requiring intensive medical care, and even (rarely) death (6).
ADVN is a nationwide research group that seeks to reduce the risk of eczema vaccinatum ("EV"), a severe and potentially deadly complication of smallpox immunization.
Eczema vaccinatum was associated with case-fatality rates of up to 10% overall and 30% to 40% in children <2 years of age (22).
 
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