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eculizumab

   Also found in: Wikipedia 0.01 sec.
eculizumab,
a monoclonal antibody.
indications This drug is used to treat proximal nocturnal hemoglobinuria, a rare, genetic form of hemolytic anemia.
contraindications Known hypersensitivity to this drug prohibits its use. Rapid discontinuation may result in serious hemolysis.
adverse effects Adverse effects of this drug include rash, dyspnea, calf or leg pain, chest pain, confusion, coughing up blood, sensitivity to light, fever, chills, persistent sore throat, mental changes, headache, nausea, vomiting, fever, stiff neck or back, mouth sores, fever blisters, and severe muscle aches. A life-threatening side effect is meningococcal infection. Common side effects are headache, nasopharyngitis, back pain, nausea, fatigue, and cough.


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Alexion is evaluating other potential indications for Soliris as well as other formulations of eculizumab for additional clinical indications, and is pursuing development of other antibody product candidates in early stages of development.
Surgeons at University Hospital, in Walsgrave, Coventry, were some of the first to trial drug Eculizumab on Craig following the transplant in October.
After the operation Craig was given new drug Eculizumab to cut the risk of any complications.
 
 
 
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