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econazole |
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econazole /econ·a·zole/ (ĕ-kon´ah-zōl) an imidazole derivative used as the nitrate salt as a broad-spectrum antifungal agent.
econazole [ikon′əzōl] a topical antifungal agent. indications It is prescribed in the treatment of tinea pedis, tinea cruris, tinea corporis, tinea versicolor, and candidiasis. contraindication Known sensitivity to this drug prohibits its use. adverse effects Among the most serious adverse effects are local irritation and hypersensitivity of the skin. econazole an imidazole antifungal agent related to miconazole; used topically as the nitrate in the treatment of fungal infections of the skin.
antifungal agent Any substance which destroys or prevents the growth of fungi. It is one of the antibiotic groups. There are several classes of antifungal drugs: Polyenes, which cause an increase in fungal cell wall permeability leading to its death. Examples: amphotericin B, natamycin, nystatin. Azoles, which act either by inhibiting the synthesis of ergosterol, a component of fungal cell wall or by causing direct wall damage. Examples: clotrimazole, econazole, fluconazole, itraconazole, ketoconazole, miconazole. Pyrimidines, which interfere with the normal function of fungal cells. Example: flucytosine. Syn antimycotic agent. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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In Switzerland, three triazoles (terconazole, itraconazole, fluconazole) and eight imidazoles (clotrimazole, miconazole, econazole, ketoconazole, tioconazole, isoconazole, oxiconazole, and fenticonazole) are in use (Documed AG 2002). Our lead product candidate, EcoNail(TM), a topically applied SEPA-based econazole lacquer for the treatment of onychomycosis, a condition commonly known as nail fungus, is currently in a Phase 2 clinical trial. He will also discuss the status of the company's two SEPA-enhanced products in clinical development - Opterone(R), a topical testosterone cream for treating male hypogonadism, and EcoNail(TM), an econazole nail lacquer for treating onychomycosis (fungal nail infections). |
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