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echovirus |
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echovirus /echo·vi·rus/ (ek´o-vi?rus) an enterovirus isolated from humans, separable into many serotypes, certain of which are associated with human disease, especially aseptic meningitis.
echovirus some viruses, which were originally considered nonpathogenic, in the family Picornaviridae, genus Enterovirus. The name is derived from the first letters of the description 'enteric cytopathogenic human orphan', but similar viruses ECBO and ECPO (for bovine and porcine, respectively, and other species) are also recognized. At the time of the isolation of the viruses the diseases they caused were not known, hence the term 'orphan', but it is now known that some of these viruses produce many different types of human disease, especially aseptic meningitis, and diarrhea and various respiratory diseases. The members of the group are now included in the enteroviruses. |
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| HPeV1 and HPeV2 were previously known as the enteroviruses echovirus 22 and 23 but were reclassified into a new genus within the family Picornaviridae after phylogenetic analysis showed that parechoviruses were distinct from other picornaviruses (1-3,8-11). A group led by researchers at Claude Bernard University in Lyon, France, has found RNA strands of a so-called echovirus in 15 of 17 spinal cord tissue samples from people who died from nonhereditary ALS. Most EVs have been implicated in aseptic meningitis, most notably echovirus (E) 30, 9, 6, and 11 and coxsackie B virus (CBV) type 5 (2); other serotypes are less frequently associated with neurologic disease. |
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