Then at the 20-week scan we were told the baby had a condition called echogenic bowel
which meant he could be born with a chromosome defect including cystic fibrosis.
Of the two more concerning findings, echogenic bowel
has been associated with trisomies, cystic fibrosis, viral infection, intrauterine growth restriction (IUGR), and fetal demise.
Radiologists use soft markers (nuchal thickening, echogenic bowel
, choroid-plexus cysts) to try to identify abnormalities.
A finding of echogenic bowel on second-trimester ultrasound typically is a transient artifact, but in some instances signals the possibility that the fetus is affected by cystic fibrosis, Dr.
The difficulty with ultrasound testing for echogenic bowel, according to Dr.
Amniocentesis should be offered when echogenic bowel is present, and genetic counseling may be warranted.
These markers included major structural anomalies, short femur or humerus, pyelectasis, nuchal fold thickening, fifth-digit abnormalities, echogenic bowel
, echogenic cardiac focus, choroid plexus cysts, ventriculomegaly, and a two-vessel umbilical cord, said Dr.
Their metaanalysis included studies that measured the true-positive, false-positive, true-negative, and false-negative results for each of eight isolated ultra sound markers for Down syndrome: nuchal-fold thickening, choroid plexus cyst, echogenic intracardiac focus, echogenic bowel
, renal pyelectasis, shortened humerus, shortened femur, and fetal structural malformations.