echinocandins


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echinocandins

A class of lipopeptide antifungal drugs that act by inhibiting glucan synthesis, thereby damaging fungal cell walls. They are effective against Candida and Aspergillus species. Examples are caspofungin (Cancidas) and micafungin.
References in periodicals archive ?
Cancidas is the first approved drug in a new class of anti-fungal agents called echinocandins, which are believed to work by disrupting the creation of gunal cell walls.
Echinocandins are available in an intravenous dosage form and have medium to high efficacy in the treatment of serious Candida infections such as invasive candidiasis, esophageal candidiasis and systemic candidiasis.
Louis, MO, USA), flucytosine (Sigma-Aldrich), and the 3 echinocandins also showed excellent activity (Table).
About MYCAMINE (micafungin sodium) for Injection MYCAMINE is a member of a class of antifungal agents, the echinocandins.
With a lower potential for interactions, the echinocandins may be ideal for combination therapy, said Dr.
GBI Research, the leading business intelligence provider has released its latest research "Antifungals Market to 2017 - Generic Erosion of Major Polyenes, Azoles, Allylamines and Echinocandins to Slow Value Growth", which provides an insight into antifungals sales and price forecasts until 2017.
Echinocandins are effective in patients with invasive candidiasis and recommended as first-line therapy, especially for patients with severe sepsis or those previously exposed to azoles or infected with Candida glabrata (1).
The echinocandins [represent] incredible improvement in the way that we treat fungal infections today," said Dr.
Expanded list of relevant drug concentration to include echinocandins and other suitable drug concentration ranges for testing dermatophytes.
Drug and Medication Industry : Antifungals Market to 2017 - Generic Erosion of Major Polyenes, Azoles, Allylamines and Echinocandins to Slow Value Growth
Establishing in vitro-in vivo correlations for Aspergillus fumigatus: the challenge of azoles versus echinocandins.
SAN DIEGO -- A new class of antifungal drugs called echinocandins can kill fluconazole-resistant Candida species rapidly with less toxicity than other treatments, Dr.