ecgonine


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Related to ecgonine: Ecgonine benzoate

ecgonine

 [ek´go-nin]
the final basic product obtained by hydrolysis of cocaine and several related alkaloids.

ec·go·nine

(ek'gō-nēn, -nin),
A product of the hydrolysis of cocaine; a topical anesthetic; basis of many coca alkaloids.

ecgonine

/ec·go·nine/ (ek´go-nin) the final basic product obtained by hydrolysis of cocaine and several related alkaloids; e. methyl ester is the major hydrolytic metabolite of cocaine detectable in blood by laboratory testing.
References in periodicals archive ?
Using this combined system, the Chemistry Unit developed a method to analyze cocaine, benzoylecgonine, cocaethylene, ecgonine methyl ester, and ecgonine in urine and blood.
Benzoic acid is a relatively common compound, so the researchers plan to look for a simple method to sense ecgonine methyl ester.
A second Entropin patent application, titled "Benzoylecgonine, Ecgonine and Ecgonidine Derivatives," is currently under consideration by the EPO.
Saliva/plasma ratios of cocaine, ecgonine methyl ester and benzoylecgonine following controlled cocaine administration.
DAS' novel protein cocaine conjugate provides for high affinity antisera for the intended targets, as contrasted to the numerous antisera and monoclonal antibodies which bind preferentially to the inactive metabolite, benzoyl ecgonine.
Sweat patch specimens were analyzed for COC, BE, EME, ecgonine ethyl ester, cocaethylene, norcocaine, norcocaethylene, m- and p-hydroxycocaine, and m- and p-hydroxybenzoylecgonine by modifying the method published by Huestis et al.
Benzoylecgonine (BE) and ecgonine methyl ester (EME), major metabolites of COC, have longer half-lives in plasma and oral fluid than does the parent drug (5,9,11-14).
The drug menu by class of substances included amphetamines, opiates (morphine-related compounds), methadone, cocaine, and cannabinoids, whereas the drug menu for identification/ quantification consisted of amphetamine, methamphetamine, morphine, codeine, 6-acetylmorphine, methadone, 1,5-dimethyl-3,3-diphenyl-2-ethylidene- pyrrolidine (EDDP), benzoylecgonine, ecgonine methyl ester, and 11-nor-9-carboxy-[[DELTA].