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A gene on chromosome 16q22.1 that encodes a calcium-dependent cell–cell adhesion glycoprotein (cadherin), which is involved in regulating cell–cell adhesions, mobility and proliferation of epithelial cells.

Molecular pathology
CDH1 loss-of-function mutations correlate with gastric, breast, colorectal, thyroid and ovarian cancer, and they are thought to contribute to cancer progression by increasing proliferation, invasion and/or metastasis. CDH1 mutation causes hereditary diffuse gastric cancer and an increased susceptibility to endometrial and ovarian cancers.


a plant form that results from the habitat in which the plant occurs and is not brought about genetically. See PHENOTYPIC PLASTICITY.
References in periodicals archive ?
Based on Figure 1, the ECAD data are similar to the demographic data for Austin as of 2009.
ECAD can concentrate on electrical design rules starting from timing requirements and routing ability that must meet given isolation classes.
ECAD systems typically operate on one PCB at a time, but most products contain multiple PCBs.
Based on Altium's solutions for collaboration and ECAD design management and Aras' suite of PLM solutions, the software developers are working on a new approach to fully integrate MCAD-ECAD PLM workflows for companies with systems engineering requirements and mechatronic product development environments.
For nearly 20 years, the Intermediate Data Format (IDF) has been the preferred file format for exchanging basic design information between the ECAD and MCAD systems that PCB layout designers and mechanical designers use to design electromechanical products.
This year ECAD was awarded Top North American Reseller in AEC Product and New Subscription Growth for 2012.
Other highlights are a STEP export for ECAD to MCAD data exchange, a copper-pour management system, enhanced support for multi-track editing, support for slotted holes in PCB pads, and improved polygon connectivity and speed.
e*ECAD's unique purchase and delivery system has distinguished the portal as the first and only company to offer ECAD software from multiple vendors in a pay-per-run time or pay-per-use model.
By incorporating these specialized engines we further enhance our ability to visualize, model and analyze in full 3D as well as provide more seamless collaboration between the ECAD and MCAD domains.
A world leader in Electronic Design Automation, Native 3D PCB design systems (Altium DesignerA, CircuitStudioA, PCBWorksA, CircuitMakerA), ECAD design data management (Altium VaultA), and embedded software development toolkits (TASKINGA), Altium Limited, has announced the next update to Altium Designer, the company's flagship PCB design tool.
Our customers expect us to know their industry, know their design needs and know the best products for the job," said ECAD President and CEO, Carole Eckert.