45) Zetola and Klausner do not recommend spinal tap for HIV-positive people with primary, secondary, or early latent syphilis "and a lack of neurologic, visual, or auditory signs or symptoms, regardless of the RPR titer or CD4 cell count.
2 million-U shots of benzathine penicillin G get the job done in people with primary, secondary, or early latent syphilis (40) (though some European countries opt for 600,000 IU of procaine penicillin for 10 to 14 days (1)).
Primary, secondary, and early latent syphilis
was diagnosed in 12, 33, and 10 patients, respectively, and 21 patients with secondary syphilis had genital lesions.
The patients' mean age was 24 years; 26% had primary syphilis, 46% had secondary syphilis, and 28% had presumed early latent syphilis
(a sexual partner in the past 12 months with confirmed syphilis).
Early latent syphilis is defined by the Centers for Disease Control and Prevention (CDC) as infection less than 12 months in duration.
CDC defines early latent syphilis as infection in less than ______ months' duration.
11) However, in the same year, the CDC also received 9,470 reports of early latent syphilis
, in which infection was probably acquired in the preceding year.
Early latent syphilis may relapse to secondary disease and is therefore considered infectious, as are primary and secondary.
Infectious syphilis Infectious syphilis includes early symptomatic syphilis plus early latent syphilis, and therefore, there was a slightly higher number of cases in 1995 (n=147) and a higher rate (0.
Hall and his colleagues performed an intensive review of state records on 30 primary, 63 secondary, and 44 early latent syphilis
cases reported in 2003, focusing on these clinical management issues:
4 million U IM in a single dose for primary, secondary, or early latent syphilis
In the second trial, 60 patients with established primary, secondary, or early latent syphilis
were randomized to one 2-g dose of azithromycin, two 2-g doses a week apart, or benzathine penicillin.