dystonia


Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.

dystonia

 [dis-to´ne-ah]
impairment of muscular tonus. adj., adj dyston´ic.
tardive dystonia a variant of tardive dyskinesia characterized by unusual posturing and movements.

dys·to·ni·a

(dis-tō'nē-ă),
A syndrome of abnormal muscle contraction that produces repetitive involuntary twisting movements and abnormal posturing of the neck, trunk, face, and extremities.
[dys- + G. tonos, tension]

dystonia

/dys·to·nia/ (-to´ne-ah) dyskinetic movements due to disordered tonicity of muscle.dyston´ic
dystonia musculo´rum defor´mans  a hereditary disorder marked by involuntary, irregular, clonic contortions of the muscles of the trunk and limbs, which twist the body forward and sideways grotesquely.

dystonia

(dĭs-tō′nē-ə)
n.
Abnormal tonicity of muscle, characterized by prolonged, repetitive muscle contractions that may cause twisting or jerking movements of the body or a body part.

dys·ton′ic (-tŏn′ĭk) adj.

dystonia

[distō′nē·ə]
Etymology: Gk, dys + tonos, tone
any impairment of muscle tone. The condition commonly involves the head, neck, and tongue and often occurs as an adverse effect of a medication.

dystonia

Neurology Involuntary, often acute movement and prolonged contraction of one or more muscles, resulting in twisting body motions, tremor, and abnormal posture Etiology Inherited, ↑ during voluntary movement, nervousness, and emotional stress; dystonias may affect the extrapyramidal system–despite lack of demonstrable lesions, task specific–eg, writer's cramp or associated with medications–especially antipsychotics or disease–eg, a form of lung cancer Location Tongue, jaw, eyes, neck, trunk, extremities, occasionally the whole body Management Dopamine, sedatives–benzodiazepines–eg diazepam, anticholinergics–eg, trihexyphenidyl, benztropine–which cause dry mouth, mydriasis, urinary retention, and visual hallucinations; surgery. See Cranial dystonia, Dopa-responsive dystonia, Focal dystonia, Idiopathic torsion dystonia, Oromandibular dystonia, Segawa's dystonia, Torsion dystonia.

dys·to·ni·a

(dis-tō'nē-ă)
A state of abnormal (either hypo- or hyper-) tonicity in any tissue, particularly skeletal muscle.
Synonym(s): torsion spasm.
[dys- + G. tonos, tension]

dystonia

A group of muscle disorders featuring variable muscle tone, muscle spasms, abnormal posture or muscle contraction, or interference with normal movement. The dystonias include wry-neck (TORTICOLLIS), WRITER'S CRAMP, spasmodic closure of the eyelids (BLEPHAROSPASM) and involuntary grimacing and chewing movements (Meige syndrome). Dystonias may be of autosomal dominant or recessive or X-linked aetiology. Botulinum toxin treatment is effective in many cases.

Dystonia

A movement disorder characterized by sustained muscle contractions that result in writhing or twisting movements and unsual body postures.

dystonia

prolonged muscle contraction, usually due to basal ganglia disease

dys·to·ni·a

(dis-tō'nē-ă)
A syndrome of abnormal muscle contraction that produces repetitive involuntary twisting movements and abnormal posturing of the neck, trunk, face, and extremities.
[dys- + G. tonos, tension]

dystonia (distō´nēə),

n a disorder or lack of tonicity.

dystonia

abnormality of muscular tonus.
References in periodicals archive ?
9) Focal limb dystonia may also respond to the antispasmodic trihexyphenidyl, but the dose must often be limited due to adverse effects such as nausea, dizziness, and anxiety.
Etiology of dystonia, duration of dystonia, and nucleus stimulated were significantly correlated with percentage change in the BFM score while the following factors we assumed did not influence outcome: age on onset of dystonia, age at surgery, gender, distribution of the dystonia, presence of associated features (such as tremor or myoclonus), abnormal preoperative MRI, prior stereotactic surgeries, type of anesthesia used.
Generalised dystonia of genetic cause (specifically DYT1 abnormality) is the most responsive to DBS.
Diagnosis of primary dystonia was confirmed according to the European Federation of Neurological Societies Consensus Statement of the Movement Disorders Society, based mainly on clinical evidence.
All patients with childhood dystonia should receive a trial of Levodopa/carbidopa--combination as it is effective in DyT5 dystonia.
Coverage of the Dystonia pipeline on the basis of target, MoA, route of administration and molecule type
The Canadian multicentre study of deep brain stimulation for cervical dystonia.
Singer's dystonia is probably underdiagnosed as a result of attributing the symptoms to improper technique, aging, or due to misdiagnosis as essential vocal tremor.
We suggest that dystonia in our case emerged from a reduced dopaminergic activity led by the serotoninergic mechanisms triggered in turn by DKP.
The aims of our study are to determine the demographic and clinical characteristics and to evaluate response to long-term botulinum toxin type A (BoNT-A) therapy and co-existent movement disorders in patients with cervical dystonia (CD) who were followed up at our clinic.
A part of the money earned from the sale of this book will be donated to The Bachmann Strauss Dystonia and Parkinson Foundation.