2 g/dL) of known isotype (62 IgG, 36 IgA, and 77 IgM) were pulled from the Mayo Clinic Dysproteinemia
Biobank (Cohort 2d).
California-based anatomic and clinical pathologist Gamble has produced a detailed guide based on 147 cases of renal involvement associated with dysproteinemia
in university and community hospital settings over some 25 years.
can cause crops of petechiae and occasionally ecchymoses.
All queries to the Laboratory Information System or Dysproteinemia
database followed a protocol on the "Natural History of Monoclonal Gammopathies," approved by the Mayo Clinic Institutional Review Board.
The 4 categories include (1) crystalline nephropathies seen in the setting of dysproteinemia
, (2) drug-induced crystalline nephropathies, (3) crystalline nephropathies related to calcium deposition, and (4) metabolic and genetic forms of crystalline nephropathy.
Spurious hyperphosphatemia in patients with dysproteinemia
is well documented (6, 7).
A serum dysproteinemia
consisting of a polyclonal hypergammaglobulinemia is present in up to 80% of patients.
9) contains several important lessons that resonate with our own clinical laboratory experience, which involved a large dysproteinemia
clinical practice, and our publications on diagnostic detection limit, which were from clinical trials and/or studies with well-defined patient groups.
She was also actively involved in the clinical immunology laboratory in the dysproteinemia
The list of 1020 patients was merged with data from the Dysproteinemia
database, which contained each patient's diagnosis, date of diagnosis, and serum and urine IFE results.
Sera from 19 patients with LCDD were obtained from the Dysproteinemia
Clinic frozen serum bank.