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dysfibrinogenemia

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dysfibrinogenemia /dys·fi·brin·o·ge·ne·mia/ (dis-fi-brin″o-jĕ-ne´me-ah) the presence in the blood of abnormal fibrinogen.
dys·fi·brin·o·ge·ne·mi·a (dsf-brn-j-nm-, -fbr-n-)
n.
A familial disorder in which fibrinogens function inadequately resulting in symptoms ranging from bleeding to thrombosis.

dysfibrinogenemia
the presence of abnormal fibrinogens in the body. An inherited dysfibrinogenemia occurs in humans and has been reported in a collie dog.

dysfibrinogenemia
A group of qualitative, usually AD, fibrinogen defects ranging in severity from innocuous to hemorrhagic diathesis; most are asymptomatic and detected by presurgical screens, given the abnormalities in coagulation parameters; these subjects suffer frequent spontaneous abortion, bleeding, poor wound healing, and thrombosis Lab Normal fibrinogen and clotting times; ↑ PT, ↑ thrombin time, ↑ reptilase time. See Fibrinogen.


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These protein deficiencies/abnormalities are genetic and include entities such as antithrombin deficiency, protein C deficiency, protein S deficiency, Factor V Leiden mutation, prothrombin 20210, and dysfibrinogenemia, among others.
Other less common causes of inherited thrombophilia are the antithrombin III, protein C and S deficiencies, and rare conditions such as plasminogen and heparin cofactor-II deficiencies and dysfibrinogenemia.
Patients with a history of afibrinogenemia, dysfibrinogenemia, or hypofibrinogenemia were excluded from this study.
 
 
 
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