dyscrasia

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dyscrasia

 [dis-kra´zhah]
a condition related to a disease or pathologic state, usually referring to an imbalance of component elements. adj., adj dyscrat´ic.
blood dyscrasia a pathologic condition of the blood, usually referring to a disorder of the cellular elements of the blood.
plasma cell d's a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment); the cells usually have plasma cell morphology, but may have lymphocytic or lymphoplasmacytic morphology. The group includes multiple myeloma, Waldenström's macroglobulinemia, the heavy chain diseases, benign monoclonal gammopathy, and immunocytic amyloidosis. Called also paraproteinemias and monoclonal gammopathies.

dys·cra·si·a

(dis-krā'zē-ă),
1. A morbid general state resulting from the presence of abnormal material in the blood, usually applied to diseases affecting blood cells or platelets.
2. Old term indicating disease.
[G. bad temperament, fr. dys- + krasis, a mixing]

dyscrasia

/dys·cra·sia/ (-kra´zhah) [Gr.] a term formerly used to indicate an abnormal mixture of the four humors; in surviving usages it is now roughly synonymous with disease or pathologic condition.
plasma cell dyscrasias  a diverse group of neoplastic diseases involving proliferation of a single clone of cells producing a serum M component (a monoclonal immunoglobulin or immunoglobulin fragment) and usually having a plasma cell morphology; it includes multiple myeloma and heavy chain diseases.

dyscrasia

(dĭs-krā′zhə, -zhē-ə)
n.
An abnormal bodily condition, especially of the blood.

dyscrasia

[diskrā′zhə]
Etymology: Gk, dys + krasis, mingling
pertaining to an abnormal condition of the blood or bone marrow, such as leukemia, aplastic anemia, or prenatal Rh incompatibility.

dyscrasia

See Blood dyscrasia, Plasma cell dyscrasia, Plasma cell dyscrasia with polyneuropathy.

dys·cra·si·a

(dis-krā'zē-ă)
Any morbid general state resulting from the presence of abnormal material in the blood, usually applied to diseases affecting blood cells or platelets.
[G. bad temperament, fr. dys- + krasis, a mixing]

dyscrasia

A vague term meaning any abnormal condition of the body.

dys·cra·si·a

(dis-krā'zē-ă)
Morbid general state resulting from presence of abnormal material in blood.
[G. bad temperament, fr. dys- + krasis, a mixing]

dyscrasia (diskrā´zhə, -zēə),

n 1. a morbid condition, especially one that involves an imbalance of component elements.
n 2. an abnormal composition of the blood, such as that found in leukemia and anemia.

dyscrasia

a morbid condition, usually referring to an imbalance of component elements.

blood dyscrasia
any abnormal or pathological condition of the blood.
References in periodicals archive ?
This investigation highlights the difficulty of elucidating whether clusters of plasma cell dyscrasias result from chance or if they have a common occupational or environmental cause.
11) The authors noted that viral infection might lead to blood dyscrasia early in illness, and that oseltamivir has been associated with a small incidence of blood dyscrasia.
We report five patients with plasma cell dyscrasia, four had C3GP and one had DDD proven by kidney biopsies.
In the event of serious side-effects such as seizure, cardiac arrhythmias, or blood dyscrasias, relevant investigations were initiated to exclude any other aetiology.
Determination of the serum levels of kappa and lambda FLC, including the FLC ratio, is a valuable immunological tool for detecting the presence of polyclonal activation and monoclonal dyscrasias of B-lymphocytes and plasma cells.
Despite the high heterogeneity of kidney disease in plasma cell dyscrasias, the risk of progression to severe organ impairment leading to renal replacement therapy is considerable; thus, it is mandatory to identify patients at risk for kidney damage at a very early stage and to institute treatment promptly.
They are a useful investigation in the diagnosis and management of plasma cell dyscrasias such as myeloma, amyloidosis and light chain deposition disease (Mayo & Johns, 2007).
Amyloidosis is a disease process in which proteinaceous material is formed and deposited in soft tissues and organs in response to various cell dyscrasias or inflammatory conditions.
amyloidosis/myeloma cast nephropathy due to paraproteins from plasma cell dyscrasias or lymphoplasmacytic proliferations
Twelve articles review recent changes in the radiotherapeutic approach to treating Hodgkin lymphoma, mature B-cell non-Hodgkin lymphomas, T-cell and NK-cell lymphomas, leukemia, and plasma cell dyscrasias.
No blood dyscrasias, vesicobullous disorder or any systemic illness are associated.
Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk.